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Kerry Rogers
🇺🇸
United States
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United States
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Clinical Trials
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Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi
Phase 2
Recruiting
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
Procedure: Biospecimen Collection
Procedure: Bone Marrow Aspiration
Procedure: Bone Marrow Biopsy
Procedure: Computed Tomography
Drug: Pirtobrutinib
Drug: Venetoclax
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First Posted Date
2024-06-20
Last Posted Date
2024-07-26
Lead Sponsor
Kerry Rogers
Target Recruit Count
30
Registration Number
NCT06466122
Locations
🇺🇸
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
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Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib Resistance
Phase 2
Withdrawn
Conditions
Chronic Lymphocytic Leukemia
Loss of Chromosome 17p
Interventions
Drug: Ibrutinib
Drug: Venetoclax
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First Posted Date
2019-05-09
Last Posted Date
2021-11-05
Lead Sponsor
Kerry Rogers
Registration Number
NCT03943342
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Bcl-2 Inhibitor GDC-0199 in Combination With Obinutuzumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or Previously Untreated Chronic Lymphocytic Leukemia
Phase 1
Active, not recruiting
Conditions
Chronic Lymphocytic Leukemia
Refractory Chronic Lymphocytic Leukemia
Interventions
Drug: Bcl-2 Inhibitor GDC-0199
Biological: Obinutuzumab
Drug: Ibrutinib
Other: Pharmacological Study
Other: Laboratory Biomarker Analysis
Other: Quality-of-Life Assessment
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First Posted Date
2015-04-28
Last Posted Date
2024-01-12
Lead Sponsor
Kerry Rogers
Target Recruit Count
87
Registration Number
NCT02427451
Locations
🇺🇸
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
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