MedPath

Luxembourg Institute of Health

🇱🇺Luxembourg
Ownership
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Established
2015-01-01
Employees
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Market Cap
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Website
https://www.lih.lu

New Sustained-Release Flucytosine Enters Phase II Trials for Cryptococcal Meningitis Amid HIV Funding Crisis

• A new sustained-release formulation of flucytosine for cryptococcal meningitis has entered Phase II trials in Malawi and Tanzania, simplifying dosing from four times to twice daily and improving administration options. • Cryptococcal meningitis, the second leading cause of death in patients with advanced HIV after tuberculosis, killed approximately 130,000 people in Africa in 2023 alone. • Recent HIV funding cuts threaten to reverse decades of progress, with experts warning of imminent stockouts of essential medicines like flucytosine and disruptions to advanced HIV disease services.
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