Ocular Therapeutix, Inc. is a biopharmaceutical company, which engages in the development and commercialization of therapies for diseases and conditions of the eye. Its product pipeline includes Dextenza, OTX-TP, and OTX-TIC. The company was founded by Amarpreet S. Sawhney and Farhad Khosravi on September 12, 2006 and is headquartered in Bedford, MA.
A phase 4 multicenter study demonstrated that perfluorohexyloctane (MIEBO) provides significant dry eye symptom relief within just 5 minutes of application, showing nearly 50% improvement that continued to increase at subsequent timepoints.
The HELIOS trial's 1-year results indicate that OTX-TKI, an intravitreal implant, can stabilize or improve non-proliferative diabetic retinopathy (NPDR).
The ocular hypertension market is expanding due to increased prevalence of conditions affecting aqueous humor outflow, leading to elevated intraocular pressure (IOP).
Ocular Therapeutix's SOL-R trial for AXPAXLI in wet AMD has enrolled 311 subjects, showing significant progress in the registrational program.
Ocular Therapeutix will present its 2025 strategic outlook at the 43rd Annual J.P. Morgan Healthcare Conference on January 13, 2025.
Ocular Therapeutix has randomized over 300 patients in the SOL-1 Phase 3 trial for AXPAXLI, an axitinib intravitreal implant, targeting wet AMD.
A phase I study of OTX-TKI, an intravitreal implant containing axitinib, demonstrated a significant reduction in injection frequency for wet AMD patients.
Ocular Therapeutix accelerates the SOL-1 Phase 3 trial for Axpaxli in wet AMD, expecting full enrollment by the end of 2024.
A Phase 3 trial of the dexamethasone intracanalicular insert (Dextenza) met its primary endpoint, significantly reducing ocular itching associated with allergic conjunctivitis.
Aldeyra Therapeutics resubmitted its NDA for reproxalap, targeting dry eye disease symptoms with both acute and chronic activity demonstrated in trials.