• A large Canadian retrospective study of 32,667 preterm infants reveals probiotics significantly reduced mortality rates, with an adjusted odds ratio of 0.62 in infants born before 34 weeks gestation.
• While probiotics showed promising survival benefits, they did not significantly decrease rates of necrotizing enterocolitis or late-onset sepsis, two common complications in preterm infants.
• The study found probiotic sepsis was rare, occurring in only 27 infants, though researchers emphasize the need for pharmaceutical-grade products and further research on specific probiotic strains.