University Health Network

🇨🇦Canada

Country: 🇨🇦Canada

Ownership: Private

Established: 1999-01-01

Employees: 10K

Market Cap: -

Website: http://www.uhn.ca

Clinical Trials

Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial)

Not Applicable

Recruiting

Conditions: Spine Disease
Spinal Cord Injuries

Interventions: Device: Continuous positive airway pressure (CPAP) therapy

First Posted Date: 2022-07-26

Last Posted Date: 2024-12-11

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 66

Registration Number: NCT05473689

Locations: 🇨🇦
KITE Toronto Research Institute, Toronto, Ontario, Canada

Feasibility of Transvenous Phrenic Nerve Stimulation for Diaphragm Protection in Acute Respiratory Failure

Not Applicable

Completed

Conditions: Acute Hypoxemic Respiratory Failure
Diaphragm Injury
Lung Injury

Interventions: Device: Lungpacer AeroPace Protect System

First Posted Date: 2022-07-19

Last Posted Date: 2024-12-11

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 20

Registration Number: NCT05465083

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

Prediction of Muscle Responsiveness to FES Therapy

Not Applicable

Active, not recruiting

Conditions: Spinal Cord Injury Cervical

Interventions: Device: Functional electrical stimulation therapy.

First Posted Date: 2022-07-18

Last Posted Date: 2024-12-11

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 10

Registration Number: NCT05462925

Locations: 🇨🇦
Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada

Prehab for Adult Spinal Deformity Surgery

Not Applicable

Active, not recruiting

Conditions: Spinal Deformity

Interventions: Behavioral: Prehabilitation

First Posted Date: 2022-07-11

Last Posted Date: 2024-12-13

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 24

Registration Number: NCT05452057

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

Diabetic Foot Care and Limb Preservation Pathway: Developmental Evaluation Study

Not yet recruiting

Conditions: Diabetic Foot
Lower Limb Wound
Diabetes
Amputation

Interventions: Other: Open-Ended Semi-Structured Interview

First Posted Date: 2022-07-06

Last Posted Date: 2022-07-18

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 70

Registration Number: NCT05446337

Durvalumab and Tremelimumab in Resectable HCC

Phase 2

Recruiting

Conditions: Hepatocellular Carcinoma

Interventions: Drug: Tremelimumab

First Posted Date: 2022-07-01

Last Posted Date: 2024-10-10

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 28

Registration Number: NCT05440864

Locations: 🇮🇹
University of Milan, Milan, Italy
🇪🇸
Clinica Universidad De Navarra, Pamplona, Spain
🇨🇦
University Health Network, Toronto, Ontario, Canada

Platform of Randomized Adaptive Clinical Trials in Critical Illness

Not Applicable

Recruiting

Conditions: Respiratory Insufficiency
Extracorporeal Membrane Oxygenation Complication
Mechanical Ventilation Pressure High

Interventions: Other: Ultra-Protective Ventilation Facilitated by Extracorporeal Support
Drug: Early Cohort corticosteroid dose
Drug: Extended Cohort corticosteroid dose
Other: Driving Pressure-Limited Ventilation (DPL)
Other: Lung-Protective Ventilation (LPV)
Drug: Usual care without routine corticosteroids
Other: Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS)
Drug: Usual care without extending corticosteroids

First Posted Date: 2022-07-01

Last Posted Date: 2024-12-11

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 6250

Registration Number: NCT05440851

Locations: 🇨🇦
University Health Network, Toronto, Canada

Characterization of Bleeding Disorders in EDS

Conditions: Classical EDS (cEDS)
Ehlers-Danlos Syndrome
EDS
Classical Ehlers-Danlos Syndrome
Hypermobile Ehlers-Danlos Syndrome
Vascular Ehlers-Danlos Syndrome
Hypermobile EDS (hEDS)
Vascular EDS (vEDS)

Interventions: Other: 20 ml venous blood collection

First Posted Date: 2022-06-28

Last Posted Date: 2023-05-09

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 45

Registration Number: NCT05434728

Locations: 🇨🇦
GoodHope EDS - Toronto General Hospital, Toronto, Ontario, Canada

PRehab tO PreparE Living Liver Donors for Enhanced Recovery

Not Applicable

Active, not recruiting

Conditions: Living Donor Liver Transplantation

Interventions: Other: Prehabilitation

First Posted Date: 2022-06-24

Last Posted Date: 2024-12-16

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 30

Registration Number: NCT05431361

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

Ultrastructural Collagen Markers in Ehlers Danlos Syndromes

Conditions: Hypermobile EDS (hEDS)
Ehlers-Danlos Syndrome
Classical Ehlers-Danlos Syndrome

Interventions: Other: Skin Biopsy

First Posted Date: 2022-06-24

Last Posted Date: 2023-11-28

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 20

Registration Number: NCT05429996

Locations: 🇨🇦
GoodHope EDS - Toronto General Hospital, Toronto, Ontario, Canada

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