University Health Network

🇨🇦Canada

Country: 🇨🇦Canada

Ownership: Private

Established: 1999-01-01

Employees: 10K

Market Cap: -

Website: http://www.uhn.ca

Clinical Trials

TOGETHER - Toronto: Trial to Evaluate the Effect of Peginterferon Lambda for the Treatment of COVID-19

Phase 3

Conditions: Sars-CoV2
Covid19

Interventions: Drug: Peginterferon Lambda-1A
Other: Placebo

First Posted Date: 2021-07-19

Last Posted Date: 2022-04-05

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 763

Registration Number: NCT04967430

Locations: 🇨🇦
Toronto General Hospital, Toronto, Ontario, Canada

Using ctDNA to Determine Therapies for Lung Cancer

Phase 2

Recruiting

Conditions: Non Small Cell Lung Cancer
Complete Surgical Resection
Circulating Tumor DNA

Interventions: Drug: Nivolumab
Drug: Pemetrexed
Drug: Gemcitabine
Drug: Cisplatin
Drug: Carboplatin
Procedure: ctDNA blood test

First Posted Date: 2021-07-19

Last Posted Date: 2024-07-22

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 66

Registration Number: NCT04966663

Locations: 🇨🇦
Princess Margaret Cancer Centre, Toronto, Ontario, Canada

ODYSSEE-vCHAT Pilot Trial for Heart Failure

Not Applicable

Completed

Conditions: Heart Failure

Interventions: Behavioral: ODYSSEE-vCHAT

First Posted Date: 2021-07-19

Last Posted Date: 2024-12-19

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 61

Registration Number: NCT04966104

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada
🇨🇦
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada

Study of Nivolumab-Ipilimumab and cfDNA in Lung Cancer

Phase 2

Active, not recruiting

Conditions: Non Small Cell Lung Cancer

Interventions: Diagnostic Test: cfDNA blood test
Drug: Nivolumab
Drug: Ipilimumab
Combination Product: Platinum-based Chemotherapy

First Posted Date: 2021-07-19

Last Posted Date: 2024-07-19

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 5

Registration Number: NCT04966676

Locations: 🇨🇦
Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Cancer Rehab Program for Allogenic Bone and Marrow Transplant Patients - CaRE-4-alloBMT

Not Applicable

Completed

Conditions: Hematologic Cancer
Allogeneic Disease
Cancer Rehabilitation

Interventions: Behavioral: CaRE-4-alloBMT plus usual care group

First Posted Date: 2021-07-19

Last Posted Date: 2023-05-09

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 80

Registration Number: NCT04966156

Locations: 🇨🇦
Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Feasibility of a Home Exercise Program to Manage Post-transplant Metabolic Syndrome

Not Applicable

Completed

Conditions: Metabolic Syndrome

Interventions: Behavioral: Exercise Training

First Posted Date: 2021-07-16

Last Posted Date: 2024-11-26

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 26

Registration Number: NCT04965142

Locations: 🇨🇦
University Health Network - Toronto General Hospital, Toronto, Ontario, Canada

Efficacy, Mechanisms and Safety of SGLT2 Inhibitors in Kidney Transplant Recipients

Phase 3

Recruiting

Conditions: Kidney Transplant Recipients
Post-transplant Diabetes Mellitus
Type 2 Diabetes

Interventions: Drug: Placebo Matching Dapagliflozin Oral Tablet
Drug: Dapagliflozin 10 MG Oral Tablet

First Posted Date: 2021-07-16

Last Posted Date: 2023-11-01

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 52

Registration Number: NCT04965935

Locations: 🇨🇦
Renal Physiology Laboratory, Toronto, Ontario, Canada

Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study

Not Applicable

Recruiting

Conditions: Anesthesia
Brain Cancer
Survival

Interventions: Drug: Propofol group
Drug: Sevoflurane group

First Posted Date: 2021-07-15

Last Posted Date: 2024-05-08

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 40

Registration Number: NCT04962672

Locations: 🇨🇦
Toronto Western Hospital/UHN, Toronto, Ontario, Canada

RESTORE in Patients Who Had COVID-19 and Close Others

Not Applicable

Conditions: Mental Health
Anxiety
Depressive Symptoms
PTSD

First Posted Date: 2021-07-12

Last Posted Date: 2021-11-05

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 20

Registration Number: NCT04958902

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Not Applicable

Recruiting

Conditions: Brain Neoplasms
Liquid Biopsy

Interventions: Procedure: Magnetic Resonance Guided Focused Ultrasound Tumor Ablation and Liquid Biopsy Acquisition
Procedure: Magnetic Resonance Guided Focused Ultrasound Thalamotomy

First Posted Date: 2021-06-25

Last Posted Date: 2023-07-27

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 50

Registration Number: NCT04940507

Locations: 🇨🇦
Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada

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