University of Victoria

Xenon Gas Inhalation Shows Promise in Reducing Alzheimer's Disease Progression in Mouse Models

4 months ago

• Inhaled xenon gas demonstrates neuroprotective effects in mouse models of Alzheimer's disease by suppressing neuroinflammation and reducing brain atrophy. • The study reveals that xenon gas modulates microglia, the brain's immune cells, promoting the clearance of amyloid plaques and improving cognitive functions. • A Phase 1 clinical trial is set to begin in early 2025 to assess the safety and efficacy of xenon gas inhalation in healthy human volunteers. • Researchers are exploring the potential of xenon gas to treat other neurological conditions, including multiple sclerosis and amyotrophic lateral sclerosis.

Anti-Obesity Drugs Show Promise in Young Children, but Long-Term Effects Remain Unknown

8 months ago

• A recent study shows that liraglutide, a GLP-1 mimic, led to a BMI decrease in children aged 6-11, offering a potential treatment for early-onset obesity. • While trials indicate significant weight loss in adolescents using drugs like semaglutide and liraglutide, concerns persist regarding long-term impacts on growth and puberty. • Experts emphasize the need for diverse studies and prolonged monitoring to address ethical considerations and potential side effects in young children using GLP-1 mimics. • The use of BMI as a metric for measuring progress has disadvantages, and weight-related health problems should be considered.