A Phase I Trial to Establish the Safety and Maximum Tolerated Dose of High-affinity Autologous BCMA-targeting Chimeric Antigen Receptor (CAR) T-cells in Patients With Relapsed and Refractory B-cell Malignancies
- Conditions
- Refractory Diffuse Large B-cell Lymphoma (DLBCL)Relapsed Diffuse Large B-cell Lymphoma (DLBCL)Multiple Myeloma in RelapseNeoplasmsMultiple Myeloma, Refractory
- Interventions
- Genetic: MDC-CAR-BCMA001 (BCMA directed CAR T-cells)
- First Posted Date
- 2023-05-01
- Last Posted Date
- 2024-06-18
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 16
- Registration Number
- NCT05836896
- Locations
- 🇩🇪
Technische Universität Dresden, NCT/UCC, Early Clinical Trial Unit, Dresden, Germany
Stress and Tooth Structure Loss in Dental Students.
- Conditions
- Tooth Wear
- First Posted Date
- 2023-03-30
- Last Posted Date
- 2023-03-30
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 25
- Registration Number
- NCT05791175
- Locations
- 🇩🇪
Department of Dental Prosthetics, Dental Division of the University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Saxony, Germany
A Retrospective Analysis of Magnetic Resonance Imaging Data for Breast Cancer Screening in the Open Consortium for Decentralized Medical Artificial Intelligence
- Conditions
- Breast Cancer
- Interventions
- Other: No intervention.
- First Posted Date
- 2023-01-26
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 25000
- Registration Number
- NCT05698056
- Locations
- 🇩🇪
Daniel Truhn, Aachen, NRW, Germany
🇩🇪Jakob Nikolas Kather, Dresden, Saxony, Germany
Evaluation and Further Development of an Artificial Intelligence-based Algorithm for Clinical Decision Support
- Conditions
- Invasive Mechanical Ventilation
- First Posted Date
- 2022-12-30
- Last Posted Date
- 2024-03-29
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 318542
- Registration Number
- NCT05668637
- Locations
- 🇪🇸
Better Care Sl, Sabadell, Spain
🇺🇸Cleveland Clinic Foundation, Cleveland, USA, Cleveland, Ohio, United States
🇪🇸Fundacion Publica Andaluza Progreso Y Salud, Sevilla, Spain
Response Prediction of Hyperthermic Intraperitoneal Chemotherapy in Gastro- Intestinal Cancer
- Conditions
- Gastric CancerColon CancerPeritoneal Carcinomatosis
- First Posted Date
- 2022-12-15
- Last Posted Date
- 2024-02-16
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 48
- Registration Number
- NCT05652348
- Locations
- 🇩🇪
Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustv Carus Dresden, Dresden, Germany
🇩🇪University Hospital Heidelberg, Heidelberg, Germany
Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery
- Conditions
- Rectum Cancer
- Interventions
- Other: Additional visualisation of surgical assistance during surgery
- First Posted Date
- 2022-12-15
- Last Posted Date
- 2024-02-16
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 40
- Registration Number
- NCT05652361
- Locations
- 🇩🇪
Department of Visceral, Thoracic and Vascular Surgery University Hospital Carl Gustav Carus Technische Universität Dresden, Dresden, Saxony, Germany
Post-COVID-19 Monitoring in Routine Health Insurance Data With Focus on Autoimmune Diseases (POINTED-AD)
- Conditions
- Virus Diseases
- Interventions
- Other: Exposed to a SARS-CoV-2 infection
- First Posted Date
- 2022-11-04
- Last Posted Date
- 2023-09-11
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 641407
- Registration Number
- NCT05606198
- Locations
- 🇩🇪
Center for Evidence-Based Healthcare, Technische Universität Dresden, Dresden, Saxony, Germany
Drainless Robot-assisted Minimally Invasive Esophagectomy
- Conditions
- Esophageal Cancer
- Interventions
- Procedure: Early removal of chest drainProcedure: Chest drain
- First Posted Date
- 2022-09-23
- Last Posted Date
- 2024-06-13
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 49
- Registration Number
- NCT05553795
- Locations
- 🇩🇪
Department of Gastrointestinal-, Thoracic and Vascular Surgery University Hospital Carl Gustav Carus Technische Universität Dresden, Dresden, Saxony, Germany
Allocating Resources for Cancer Care in Times of the Sars-CoV-2 Outbreak. Health Care Research
- Conditions
- Colorectal Cancer (CRC) and Pancreatic Cancer (PaCa)
- First Posted Date
- 2022-07-29
- Last Posted Date
- 2022-07-29
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 6500
- Registration Number
- NCT05479292
- Locations
- 🇩🇪
ZEGV, Dresden, Saxony, Germany
A Single-arm Trial of Atezolizumab/Platinum/Etoposide for the Treatment of Advanced Large-cell Neuroendocrine Cancer of the Lung
- Conditions
- Large Cell Neuroendocrine Carcinoma of the Lung
- Interventions
- First Posted Date
- 2022-07-22
- Last Posted Date
- 2025-01-20
- Lead Sponsor
- Technische Universität Dresden
- Target Recruit Count
- 67
- Registration Number
- NCT05470595
- Locations
- 🇩🇪
Charité - Universitätsklinikum Berlin Centrum 12, Medizinische Klinik, Berlin, Germany
🇩🇪Evangelische Lungenklinik, Berlin, Germany
🇩🇪Universitätsklinikum Dresden, Medizinische Klinik 1, Dresden, Germany