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Ichnos Sciences SA

🇨🇭Switzerland
Ownership
Subsidiary
Employees
-
Market Cap
-
Website
http://www.glenmarkpharma.com

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma

Phase 1
Recruiting
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
First Posted Date
2023-05-17
Last Posted Date
2024-12-19
Lead Sponsor
Ichnos Sciences SA
Target Recruit Count
80
Registration Number
NCT05862012
Locations
🇺🇸

Standford Cancer Institute, Palo Alto, California, United States

🇦🇺

Concord Hospital, Concord, New South Wales, Australia

🇺🇸

Montefiore Medical Center, Bronx, New York, United States

and more 6 locations

Phase 1/2 Study of ISB 1442 in Relapsed/Refractory Multiple Myeloma

Phase 1
Terminated
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
Drug: ISB 1442 SC injection escalating doses
Drug: ISB 1442 SC injection at RP2D
First Posted Date
2022-06-22
Last Posted Date
2025-01-17
Lead Sponsor
Ichnos Sciences SA
Target Recruit Count
29
Registration Number
NCT05427812
Locations
🇺🇸

University of Miami - Sylvester Comprehensive Cancer Center, Miami, Florida, United States

🇺🇸

The University of Chicago Medical Center (UCMC) Duchossois Center for Advanced Medicine (DCAM), Chicago, Illinois, United States

🇺🇸

Barbara Ann Karmanos Cancer Institute - Karmanos Cancer Center - Main Campus, Detroit, Michigan, United States

and more 12 locations

Study of ISB 1302 (CD3 Bispecific Ab) in HER2-positive Metastatic Breast Cancer

Phase 1
Terminated
Conditions
Breast Cancer
Interventions
Biological: ISB 1302 250 ng/kg
Biological: ISB 1302 325 ng/kg
Biological: ISB 1302 325 ng/kg-D1;425 ng/kg -D8,D15,D22
Biological: ISB 1302 escalating doses,1200 ng/kg D15,22
Biological: ISB 1302 325 ng/kg-D1;550 ng/kg -D8,D15,D22
Biological: ISB 1302 325ng/kg D1;550 ng/kg D8;900 ng/kg D15,22
Biological: ISB 1302 325ng/kgD1;550 ng/kg D8;700 ng/kgD15,22
Biological: ISB 1302 at the MTD and/or RP2D dose
First Posted Date
2019-06-12
Last Posted Date
2021-05-24
Lead Sponsor
Ichnos Sciences SA
Target Recruit Count
1
Registration Number
NCT03983395
Locations
🇺🇸

Ichnos Investigational Site 3, Philadelphia, Pennsylvania, United States

🇺🇸

Ichnos Investigational Site 1, Gilbert, Arizona, United States

🇺🇸

Ichnos Investigational Site 4, Louisville, Kentucky, United States

and more 2 locations

Phase 2b Study to Evaluate the Efficacy and Safety of ISB 830 in Adults With Moderate to Severe Atopic Dermatitis

Phase 2
Completed
Conditions
Moderate to Severe Atopic Dermatitis
Interventions
Drug: ISB 830 - Part 2 Group 5
Drug: ISB 830 - Part 1 Group 2
Drug: ISB 830 - Part 1 Group 3
Drug: Placebo - Part 1 Group 4
Drug: ISB 830 - Part 1 Group 1
Drug: Placebo - Part 2 Group 6
First Posted Date
2018-06-26
Last Posted Date
2022-08-23
Lead Sponsor
Ichnos Sciences SA
Target Recruit Count
462
Registration Number
NCT03568162
Locations
🇺🇸

Ichnos Investigational Site 144, Las Vegas, Nevada, United States

🇺🇸

Ichnos Investigational Site 148, Lake City, Florida, United States

🇺🇸

Ichnos Investigational Site 129, Birmingham, Alabama, United States

and more 80 locations

Study of ISB 1342, a CD38/CD3 Bispecific Antibody, in Subjects With Previously Treated Multiple Myeloma

Phase 1
Completed
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
Biological: ISB 1342
First Posted Date
2017-10-13
Last Posted Date
2024-06-13
Lead Sponsor
Ichnos Sciences SA
Target Recruit Count
81
Registration Number
NCT03309111
Locations
🇺🇸

Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States

🇺🇸

Hackensack University Medical Center, Hackensack, New Jersey, United States

🇺🇸

Duke Clinical Research Institute, Durham, North Carolina, United States

and more 17 locations

Phase 1 Study of Single Agent GBR 1302 in Subjects With HER2 Positive Cancers

Phase 1
Terminated
Conditions
HER2 Expressing Solid Tumours
Interventions
Drug: CD3/HER2 bispecific monoclonal antibody
First Posted Date
2016-07-12
Last Posted Date
2020-10-09
Lead Sponsor
Ichnos Sciences SA
Target Recruit Count
36
Registration Number
NCT02829372
Locations
🇺🇸

Glenmark Investigational Site 204, Fairway, Kansas, United States

🇩🇪

Glenmark Investigational Site 103, Berlin, Germany

🇩🇪

Glenmark Investigational Site 102, Cologne, Germany

and more 5 locations

To Assess the Safety and Activity of GBR 830, Compared to Placebo, in Adults With Moderate-to-severe Atopic Dermatitis

Phase 2
Completed
Conditions
Atopic Dermatitis
Interventions
Biological: GBR 830
Biological: Placebo
First Posted Date
2016-02-17
Last Posted Date
2020-05-18
Lead Sponsor
Ichnos Sciences SA
Target Recruit Count
64
Registration Number
NCT02683928
Locations
🇺🇸

Glenmark Investigational Site 5, Los Angeles, California, United States

🇺🇸

Glenmark Investigational Site 14, Rogers, Arkansas, United States

🇺🇸

Glenmark Investigational Site 15, Tampa, Florida, United States

and more 14 locations
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