CDC ENTEBBE

A comprehensive analysis of 19 clinical trials involving 6,506 patients found tramadol provides only minimal pain relief that falls below clinically meaningful thresholds for chronic pain management.

Biomea Fusion's Phase II COVALENT-111 study demonstrates that icovamenib, a menin inhibitor, provides sustained HbA1c reductions lasting nine months after treatment completion in type 2 diabetes patients.

The CDC's Advisory Committee on Immunization Practices voted 8-3 to recommend against using Merck's combined MMRV vaccine for first doses in children age 4 and younger, citing double the rate of febrile seizures compared to separate shots.

LinusBio published research in The Lancet's eBioMedicine demonstrating a novel hair-based biomarker for ALS detection using copper-related elemental patterns.

A randomized clinical trial of 249 participants found that a single injection of benzathine penicillin G achieved 76% serologic response compared to 70% with the three-dose regimen at 6 months.

A qualitative analysis of the OPTIMIZE-CKD study found broad patient support for collaborative chronic kidney disease management between primary care providers and nephrologists.

pH-D Feminine Health has launched the first FDA-cleared Phase 3 clinical trial to validate boric acid suppositories as a treatment for yeast infections, marking a critical milestone in women's health research.

Leading medical organizations including the American Medical Association, American Academy of Pediatrics, and Infectious Diseases Society of America have been barred from CDC vaccine advisory workgroups.

Vaccine maker Bavarian Nordic has agreed in principle to a roughly $3 billion take-private offer from private equity firms Nordic Capital and Permira, with completion expected in the fourth quarter.

A federal judge has halted the Trump administration's mass layoffs at the Department of Health and Human Services, ruling the cuts likely violated federal law and caused irreparable harm.