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OMEROS CORPORATION

🇺🇸United States
Ownership
-
Established
1994-01-01
Employees
-
Market Cap
$238.1M
Website
http://www.omeros.com/

Clinical Trials

57

Active:26
Completed:17

Trial Phases

3 Phases

Phase 1:25
Phase 2:11
Phase 3:13

Drug Approvals

1

FDA:1

Drug Approvals

Omidria

Approval Date
Dec 14, 2022
FDA

Clinical Trials

Distribution across different clinical trial phases (49 trials with phase data)• Click on a phase to view related trials

Phase 1
25 (51.0%)
Phase 3
13 (26.5%)
Phase 2
11 (22.4%)

Long-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria

Phase 2
Recruiting
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
First Posted Date
2024-03-07
Last Posted Date
2024-03-07
Lead Sponsor
Omeros Corporation
Target Recruit Count
25
Registration Number
NCT06298955
Locations
🇬🇧

Omeros Investigational Site, Leeds, United Kingdom

Safety and Efficacy Study of OMS906 in Patients With C3G and ICGN

Phase 2
Recruiting
Conditions
C3 Glomerulopathy
Idiopathic Immune Complex-Mediated Glomerulonephritis
Interventions
First Posted Date
2024-01-17
Last Posted Date
2024-04-18
Lead Sponsor
Omeros Corporation
Target Recruit Count
20
Registration Number
NCT06209736
Locations
🇬🇧

Omeros Investigational Site, Newcastle Upon Tyne, United Kingdom

Safety and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria Patients With a Sub-optimal Response to Ravulizumab

Phase 2
Active, not recruiting
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
First Posted Date
2023-08-02
Last Posted Date
2025-01-08
Lead Sponsor
Omeros Corporation
Target Recruit Count
12
Registration Number
NCT05972967
Locations
🇬🇧

Omeros Investigational Site, Leeds, United Kingdom

Study of the Safety and Efficacy of OMS906 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Phase 1
Recruiting
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
First Posted Date
2023-06-05
Last Posted Date
2023-06-05
Lead Sponsor
Omeros Corporation
Target Recruit Count
10
Registration Number
NCT05889299
Locations
🇺🇦

Omeros Investigational Site, Kyiv, Ukraine

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

Phase 2
Recruiting
Conditions
Thrombotic Microangiopathies
Hematopoietic Stem Cell Transplantation
First Posted Date
2023-05-11
Last Posted Date
2025-03-25
Lead Sponsor
Omeros Corporation
Target Recruit Count
18
Registration Number
NCT05855083
Locations
🇪🇸

Omeros Investigational Site, Pamplona, Spain

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News

Omeros Restructures $80.5 Million in Debt, Significantly Reducing Near-Term Financial Obligations

Omeros Corporation has entered into agreements to exchange $70.5 million of its 2026 Convertible Notes for new 2029 Convertible Notes with a 9.50% interest rate, extending debt maturity by three years.

IgA Nephropathy Pipeline Shows Robust Growth with 30+ Therapies in Development

DelveInsight's 2025 pipeline analysis reveals over 30 companies developing 30+ therapies for IgA nephropathy treatment, representing a robust therapeutic landscape.

Omeros Forms Elite Clinical Steering Committee to Advance Novel AML Therapeutic Program

Omeros Corporation has established an Oncology Clinical Steering Committee comprising eight distinguished leukemia experts from leading cancer centers to guide its OncotoX-AML program development.

Omeros Advances Zaltenibart Phase 3 Trials for PNH with Potential Superiority Over Current Treatments

Omeros Corporation has initiated site activation for its Phase 3 clinical trials of zaltenibart (OMS906) in paroxysmal nocturnal hemoglobinuria (PNH), with data for regulatory submission expected in Q4 2026.

Narsoplimab Shows Promising Real-World Outcomes in TA-TMA Patients at 2025 Tandem Meetings

Omeros Corporation will present real-world data from 128 transplant patients treated with narsoplimab for TA-TMA under an expanded access program at the 2025 Tandem Meetings in Honolulu.

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