A recent study suggests active monitoring may be a safe alternative to standard treatment for low-risk ductal carcinoma in situ (DCIS).
Researchers have identified the NLRP3 inflammasome as a key driver of hyper-progression in melanoma patients treated with checkpoint inhibitors.
Dual immunotherapy or chemoimmunotherapy may offer improved outcomes for NSCLC patients with KRAS/STK11 mutations compared to single-agent PD-L1 inhibitors.
Estrogen has been found to promote tumor growth in estrogen receptor-negative breast cancers and other cancers like melanoma and colon cancer by suppressing the immune system.
Mirvetuximab soravtansine (MIRV) demonstrates a 51.9% overall response rate in patients with platinum-sensitive ovarian cancer (PROC) in the PICCOLO trial.
A phase one study of a dendritic cell vaccine combined with intensified temozolomide showed promising survival benefits in glioblastoma patients.