University of Pavia

A millifluidic bioreactor enables long-term culture of primary lymphocytes and CD34+ hematopoietic cells, detecting tumorigenic expansion. The Miniaturized Optically Accessible Bioreactor (MOAB) platform, with silk-based framework, supports cell viability for up to three months and detects as few as 100 tumorigenic cells among 100,000 primary cells.