University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Redirected High Affinity Gag-Specific Autologous T Cells for HIV Gene Therapy

Phase 1

Completed

Conditions: HIV Infections

Interventions: Biological: WT-gag-TCR modified T cells
Biological: α/6-gag-TCR modified T cells
Other: STI or Drug Holiday

First Posted Date: 2009-10-07

Last Posted Date: 2019-10-10

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 2

Registration Number: NCT00991224

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Plasma Exchange and Glucocorticoids for Treatment of Anti-Neutrophil Cytoplasm Antibody (ANCA) - Associated Vasculitis

Phase 3

Completed

Conditions: Microscopic Polyangiitis (MPA)
Granulomatosis With Polyangiitis (Wegener's) (GPA)

Interventions: Procedure: Plasma Exchange
Other: No Plasma Exchange
Drug: Glucocorticoids [Standard Dose]
Drug: Glucocorticoids [Reduced Dose]

First Posted Date: 2009-09-30

Last Posted Date: 2020-05-26

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 704

Registration Number: NCT00987389

Locations: 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
🇺🇸
University of North Carolina, Chapel Hill, North Carolina, United States
🇺🇸
University of Virginia, Charlottesville, Virginia, United States

and more 95 locations

Evaluation of an Algorithm to Reduce Antibiotic Prescribing for Acute Bronchitis

Not Applicable

Completed

Conditions: Acute Respiratory Tract Infection

Interventions: Behavioral: Decision Support for ARI Management

First Posted Date: 2009-09-22

Last Posted Date: 2016-11-28

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 3300

Registration Number: NCT00981994

Brain Tissue Oxygen Monitoring in Traumatic Brain Injury (TBI)

Phase 2

Completed

Conditions: Severe Traumatic Brain Injury

Interventions: Device: Management protocol based on ICP values only.
Device: Management protocol based on pBrO2 and ICP values.

First Posted Date: 2009-09-10

Last Posted Date: 2019-09-26

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 122

Registration Number: NCT00974259

Locations: 🇺🇸
University of Miami/Jackson Memorial Hospital, Miami, Florida, United States
🇺🇸
Ohio State University, Columbus, Ohio, United States
🇺🇸
Temple University, Philadelphia, Pennsylvania, United States

and more 7 locations

Epidemiology and Prevention of Methicillin Resistant Staphylococcus Aureus (MRSA) Transmission in the Community

Not Applicable

Completed

Conditions: MRSA - Methicillin Resistant Staphylococcus Aureus Infection

Interventions: Drug: Supervised Decolonization
Drug: Unsupervised Decolonization

First Posted Date: 2009-08-27

Last Posted Date: 2019-07-05

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 223

Registration Number: NCT00966446

Locations: 🇺🇸
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, United States
🇺🇸
Hershey Medical Center, Hershey, Pennsylvania, United States
🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

and more 1 locations

Lifestyle Modification and Blood Pressure Study

Phase 2

Completed

Conditions: High Blood Pressure

Interventions: Behavioral: Yoga exercise program
Behavioral: Blood pressure education/walking program

First Posted Date: 2009-08-25

Last Posted Date: 2017-02-15

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 147

Registration Number: NCT00964847

Locations: 🇺🇸
Hospital at the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Prevention of Relapse & Recurrence of Bipolar Depression

Phase 4

Completed

Conditions: Bipolar Disorder

Interventions: Drug: Lithium / Placebo
Drug: Lithium / Fluoxetine

First Posted Date: 2009-08-19

Last Posted Date: 2020-10-19

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 177

Registration Number: NCT00961961

Locations: 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
🇺🇸
Depression Research Unit, Philadelphia, Pennsylvania, United States

Think Health! A Personal Weight Management Program

Not Applicable

Completed

Conditions: Obesity

Interventions: Behavioral: Think Health! program
Behavioral: Basic Plus program

First Posted Date: 2009-08-14

Last Posted Date: 2016-08-17

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 261

Registration Number: NCT00959608

Locations: 🇺🇸
Greenhouse Internists, Philadelphia, Pennsylvania, United States
🇺🇸
Einstein Community Health Associates, Philadelphia, Pennsylvania, United States
🇺🇸
Northeast Family Medicine, Philadelphia, Pennsylvania, United States

and more 2 locations

Prophylactic Use of Antibiotics for Through and Through Lacerations of the Lip

Not Applicable

Terminated

Conditions: Through-and-through Lip Lacerations

Interventions: Drug: placebo
Drug: keflex

First Posted Date: 2009-08-12

Last Posted Date: 2019-04-16

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 4

Registration Number: NCT00957827

Locations: 🇺🇸
Hopital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Assessment of High Dose Transdermal Nicotine for Fast Metabolizers of Nicotine

Phase 2

Completed

Conditions: Nicotine Dependence

Interventions: Drug: Nicoderm CQ transdermal nicotine
Drug: placebo

First Posted Date: 2009-08-11

Last Posted Date: 2014-08-15

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 87

Registration Number: NCT00956943

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

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