University of Pennsylvania

The first patients at the University of Pennsylvania who received experimental CAR T cell therapy for leukemia showed remarkable results, with the first patient's biopsy showing no evidence of leukemia.

Doctors plan to request FDA approval this winter for a clinical trial testing CRISPR base editing in seven different urea cycle disorders, following the successful treatment of baby KJ with CPS1 deficiency.

A phase 2a trial of CAN-2409 viral immunotherapy showed median overall survival of 24.5 months in 46 patients with advanced NSCLC who failed immune checkpoint inhibitor therapy.

Researchers at the University of Gothenburg found that semaglutide, a diabetes and weight loss medication, reduced cocaine self-administration by 26% in rats compared to control animals.

A first-of-its-kind clinical trial demonstrated that repurposed cancer drugs can effectively target dormant breast cancer cells, clearing them in 80% of participants and potentially preventing cancer recurrence.

Northwest Biotherapeutics has completed its acquisition of Advent BioServices Ltd., making it a wholly owned subsidiary to enable fully integrated operations and manufacturing scale-up.

The Wistar Institute received a five-year, $17 million NIH grant to launch the iCure Consortium, developing individualized cure regimens for HIV through personalized medicine approaches.

The FDA has approved expansion of Aquedeon Medical's IDE clinical trial for the Duett Vascular Graft System, increasing enrollment from the initial study to up to 90 patients across additional U.S. clinical sites.

Pre-treatment genetic testing for DPYD and UGT1A1 variants reduced severe chemotherapy side effects from 65% to 38% in gastrointestinal cancer patients with genetic variants.

Dispatch Bio, a new biotech company formed through collaboration between Arch Venture Partners and the Parker Institute for Cancer Immunotherapy, has raised $216 million to develop a universal solid tumor treatment approach.