University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Hypertension Chronobiome

Recruiting

Conditions: Hypertension

Interventions: Other: Ambulatory blood pressure measurements

First Posted Date: 2018-07-26

Last Posted Date: 2024-08-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 150

Registration Number: NCT03598894

Locations: 🇺🇸
Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania, Philadelphia, Pennsylvania, United States

A Personalized Prehabilitation Intervention In Elective Joint Replacement Surgery

Not Applicable

Suspended

Conditions: Arthropathy of Knee Joint
Arthropathy of Hip Joint

Interventions: Behavioral: personalized prehabilitation

First Posted Date: 2018-07-26

Last Posted Date: 2024-07-09

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 28

Registration Number: NCT03601728

Locations: 🇺🇸
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States

Effects of Metformin During Nicotine Withdrawal

Phase 2

Completed

Conditions: Smoking
HIV-1-infection

Interventions: Drug: Metformin
Drug: Placebo

First Posted Date: 2018-07-20

Last Posted Date: 2021-03-26

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 80

Registration Number: NCT03593538

Locations: 🇺🇸
Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania, Philadelphia, Pennsylvania, United States

DC Vaccine in Pancreatic Cancer

Phase 1

Completed

Conditions: Pancreatic Ductal Adenocarcinoma

Interventions: Drug: mDC3/8-KRAS Vaccine

First Posted Date: 2018-07-19

Last Posted Date: 2024-05-07

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 29

Registration Number: NCT03592888

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Timed Aspirin Chronobiome Study

Early Phase 1

Not yet recruiting

Conditions: Healthy

Interventions: Drug: Aspirin 81 mg
Drug: Celecoxib 200mg capsule

First Posted Date: 2018-07-18

Last Posted Date: 2024-07-09

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 60

Registration Number: NCT03590821

Locations: 🇺🇸
Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania, Philadelphia, Pennsylvania, United States

MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 1

Terminated

Conditions: Ovarian Cancer
Fallopian Tube Cancer
Primary Peritoneal Carcinoma

Interventions: Drug: MOv19-BBz CAR T cells
Device: Alpha Folate Receptor expression test

First Posted Date: 2018-07-13

Last Posted Date: 2024-04-12

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 46

Registration Number: NCT03585764

Locations: 🇺🇸
University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States

Prehabilitation Intervention to Maximize Early Recovery (PRIMER) in Liver Transplantation

Not Applicable

Completed

Conditions: Liver Diseases
Frailty
End Stage Liver Disease

Interventions: Device: Nokia GO Wearable StepTracker
Other: Medication Reminder
Other: Weekly Check-in appointment with study team or provider

First Posted Date: 2018-07-12

Last Posted Date: 2023-01-11

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 30

Registration Number: NCT03584646

Locations: 🇺🇸
Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania, United States

Psychological Intervention to Reduce Weight Bias Internalization

Not Applicable

Completed

Conditions: Obesity
Weight Loss
Stigmatization

Interventions: Behavioral: BWL
Behavioral: BIAS

First Posted Date: 2018-06-28

Last Posted Date: 2020-10-23

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 72

Registration Number: NCT03572218

Locations: 🇺🇸
The University of Pennsylvania Center for Weight and Eating Disorders, Philadelphia, Pennsylvania, United States

A Field Experiment to Assess the Demand for HIV Self-Tests in Zimbabwe

Not Applicable

Completed

Conditions: HIV/AIDS

Interventions: Behavioral: Vouchers for HIV self-testing kits

First Posted Date: 2018-06-18

Last Posted Date: 2019-02-28

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 4000

Registration Number: NCT03559959

Locations: 🇿🇼
Zimbabwe and the Centre for Sexual Health and HIV/AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe

Furosemide for Accelerated Recovery of Blood Pressure Postpartum

Phase 2

Completed

Conditions: Hypertension, Pregnancy-Induced

Interventions: Drug: Oral furosemide
Drug: Placebo Oral Tablet

First Posted Date: 2018-06-14

Last Posted Date: 2020-09-10

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 384

Registration Number: NCT03556761

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

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