UNIVERSITY OF SOUTHERN CALIFORNIA

New medical technology uses fluorescent light to detect hidden bacteria in wounds, potentially improving healing and reducing amputations, particularly for diabetic foot wounds.

A hormonal gel for male birth control, tested in a phase 2 trial, showed promising results with 86% of participants achieving sperm suppression within 12 weeks. The gel combines testosterone and Nestorone, aiming for fewer side effects. Despite interest, funding challenges hinder progress. Nonhormonal options are also in development, reflecting growing demand for male contraception.

A phase 2 trial of a hormonal gel for male contraception showed 86% sperm suppression in 222 men, achieving effective contraception in eight weeks. The gel combines testosterone and Nestorone, acting faster with less testosterone. Interest in male contraceptives is rising, with surveys indicating willingness among men to use new methods.

Doxycycline post-exposure prophylaxis (doxyPEP) significantly reduced STIs among gay and bisexual men and transgender women in San Francisco, with notable decreases in chlamydia and syphilis but less impact on gonorrhoea. Real-world data and clinical trials align, showing doxyPEP's effectiveness, despite concerns over antimicrobial resistance.

Michigan Institute of Urology celebrated over 50 years, highlighting 2023 milestones: clinical trials for urologic cancers, opening REDEEM Sexual Wellness Center, completing IR Centers for minimally invasive treatments, attracting top talent, and hosting a record-breaking Men’s Health Event. Plans for 2024 include opening an Ambulatory Surgery Center, expanding staff, and advancing genetic testing for cancer.

The TACTIC-3 trial investigates TAC101-CLDN18.2's safety and efficacy for CLDN18.2+ solid tumors, showing tumor regression in models with low toxicity. It's recruiting for gastric, esophageal, pancreatic, ovarian, and lung cancers at multiple centers including Dana Farber and MD Anderson.

2022 marked a transition in the COVID-19 pandemic, with advancements in cancer research including 40 FDA oncology drug approvals and promising immunotherapy trials. Despite progress, challenges remain in cancer prevention and treatment. The AACR emphasized the importance of e-cigarette regulation and highlighted future directions in cancer research, including immunotherapy, precision medicine, and addressing health disparities.

Childhood obesity has risen sharply, with 14.7 million U.S. children affected, leading to serious health risks. The American Academy of Pediatrics updated obesity guidelines in 2023. Obesity, especially severe, increases risks of liver disease, diabetes, and heart issues. Addressing obesity requires family-wide healthful habits, not just focusing on weight.

Omicron may be more detectable in saliva than nasal samples, prompting some to recommend throat swabs before nasal swabs for COVID-19 rapid tests, despite FDA and manufacturer advice against at-home throat swabs. Studies suggest saliva tests could detect Omicron earlier, especially in vaccinated individuals, though throat swabs might also pick up nasal drainage. Proper technique is crucial for throat swabbing to avoid contamination and ensure accuracy.