• The National Cancer Center Japan will conduct a Phase I/II basket trial of Boron Neutron Capture Therapy (BNCT) for unresectable and recurrent thoracic malignant solid tumors.
• This trial is the first of its kind to evaluate BNCT across multiple thoracic cancer types, aiming to expedite development by grouping cancers with shared organs at risk.
• The study will assess the safety and efficacy of BNCT, along with the utility of [18F]F-BPA PET imaging in determining patient suitability for BNCT.
• The collaboration involves Sumitomo Heavy Industries, STELLA PHARMA CORPORATION, and Cancer Intelligence Care Systems, with the trial period extending until October 2028.