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UNIVERSITY OF MARYLAND, COLLEGE PARK

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Maryland Stem Cell Research Fund Allocates $18 Million to Advance Regenerative Medicine Research

• The Maryland Stem Cell Research Commission has awarded over $18 million in grants to 52 investigators working on nearly 50 different medical conditions including sickle cell anemia, diabetes, and various neurological disorders. • Funding recipients include innovative companies like Seraxis Inc. and Britecyte Inc., alongside researchers from major Maryland institutions, with the University of Maryland Eastern Shore receiving its first-ever stem cell research grant. • Since its establishment in 2006, the MSCRF has invested over $200 million in more than 650 projects, generating $525 million in economic activity and creating over 2,000 jobs across Maryland.

NIH's TrialGPT AI Algorithm Streamlines Clinical Trial Matching

• The NIH has developed TrialGPT, an AI algorithm designed to efficiently match patients to relevant clinical trials listed on ClinicalTrials.gov. • TrialGPT demonstrated accuracy comparable to human clinicians in assessing eligibility criteria, while reducing screening time by 40% in a pilot study. • The AI tool aims to reduce barriers to clinical trial enrollment, potentially increasing access for underrepresented populations and improving recruitment. • Awarded the Director's Challenge Innovation Award, TrialGPT will undergo further evaluation to ensure fairness and real-world performance across diverse populations.

NIH's TrialGPT AI Algorithm Streamlines Clinical Trial Matching for Patients

• Researchers at the NIH developed TrialGPT, an AI algorithm, to efficiently match patients with relevant clinical trials listed on ClinicalTrials.gov. • TrialGPT analyzes patient data and identifies suitable trials, providing a ranked list with explanations of eligibility criteria, mirroring clinician accuracy. • A pilot study showed TrialGPT reduced clinician screening time by 40% while maintaining accuracy in matching patients to appropriate trials. • The AI tool aims to improve clinical trial recruitment, particularly for underrepresented populations, and accelerate medical research advancements.
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