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St. Renatus, LLC

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Comparison of Anesthetic Efficacy of Bilateral and Unillateral Application of Kovacaine Mist in Healthy Volunteers

Phase 1

Completed

Conditions: Anesthesia

Interventions: Drug: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
Drug: Placebo spray

First Posted Date: 2015-05-29

Last Posted Date: 2016-11-10

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 48

Registration Number: NCT02457806

Locations: 🇺🇸
Jean Brown Research, Salt Lake City, Utah, United States

Safety and Pharmacokinetics of Kovacaine Nasal Spray in Pediatric Subjects

Phase 2

Completed

Conditions: Anesthesia

Interventions: Drug: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%

First Posted Date: 2013-09-30

Last Posted Date: 2015-06-08

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 18

Registration Number: NCT01952990

Locations: 🇺🇸
AXIS Clinical Trials Research Center, Los Angeles, California, United States

Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Pediatric Patients

Phase 3

Completed

Conditions: Anesthesia

Interventions: Drug: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
Drug: Placebo

First Posted Date: 2013-05-01

Last Posted Date: 2017-08-30

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 90

Registration Number: NCT01844830

Locations: 🇺🇸
Big Grins, Fort Collins, Colorado, United States
🇺🇸
Center for Dental Research Loma Linda University School, Loma Linda, California, United States

Safety and Pharmacokinetics of Kovacaine Nasal Spray (24 Hour Blood Collection)

Phase 2

Completed

Conditions: Anesthesia

Interventions: Drug: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%

First Posted Date: 2013-03-08

Last Posted Date: 2017-08-30

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 24

Registration Number: NCT01807624

Locations: 🇺🇸
Jean Brown Research, Salt Lake City, Utah, United States

Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Adults

Phase 3

Completed

Conditions: Anesthesia

Interventions: Drug: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
Drug: Placebo

First Posted Date: 2012-12-10

Last Posted Date: 2017-01-31

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 150

Registration Number: NCT01745380

Locations: 🇺🇸
Center for Dental Research Loma Linda University School, Loma Linda, California, United States
🇺🇸
University of Maryland, Baltimore, Baltimore, Maryland, United States
🇺🇸
University of Pennsylvania, School of Dental Medicine, Philadelphia, Pennsylvania, United States

Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth in Adults

Phase 3

Completed

Conditions: Anesthesia

Interventions: Drug: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
Drug: Placebo
Drug: Tetracaine HCl 3%

First Posted Date: 2012-10-19

Last Posted Date: 2017-08-30

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 110

Registration Number: NCT01710787

Locations: 🇺🇸
University of Buffalo, Buffalo, New York, United States
🇺🇸
Jean Brown Research, Salt Lake City, Utah, United States
🇺🇸
Family and Cosmetic Dentistry, Salt Lake City, Utah, United States

Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects

Phase 2

Completed

Conditions: Anesthesia

Interventions: Drug: 120uL of Kovacaine Mist
Drug: 400uL of Kovacaine Mist
Drug: 200uL of Kovacaine Mist

First Posted Date: 2012-10-05

Last Posted Date: 2017-08-30

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 48

Registration Number: NCT01701505

Locations: 🇺🇸
Big Grins, Fort Collins, Colorado, United States

Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth

Phase 3

Terminated

Conditions: Anesthesia

Interventions: Drug: Tetracaine HCl 3%
Drug: Tetracaine HCl 3% and oxymetazoline HCl 0.05%
Drug: Placebo

First Posted Date: 2012-08-09

Last Posted Date: 2017-09-05

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 26

Registration Number: NCT01660893

Locations: 🇺🇸
University of Maryland, Baltimore, Baltimore, Maryland, United States
🇺🇸
Jean Brown Research, Salt Lake City, Utah, United States
🇺🇸
Family and Cosmetic Dentistry, Salt Lake City, Utah, United States

Open-Label Study of Efficacy and Recommended Dose of Kovacaine Mist for Anesthetizing Maxillary Teeth

Phase 2

Completed

Conditions: Anesthesia

Interventions: Drug: Kovacaine Mist 0.1 mL x 4 sprays
Drug: Kovacaine Mist 0.2 mL x 2 sprays
Drug: Kovacaine Mist 0.2 mL x 1 spray

First Posted Date: 2011-11-24

Last Posted Date: 2016-12-29

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 30

Registration Number: NCT01479517

Locations: 🇺🇸
Rock Dental Clinic, Colorado Springs, Colorado, United States

Dose-Escalation Safety and Pharmacokinetic Study of K305

Phase 2

Completed

Conditions: Anesthesia

Interventions: Drug: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%

First Posted Date: 2011-02-25

Last Posted Date: 2017-08-31

Lead Sponsor: St. Renatus, LLC

Target Recruit Count: 12

Registration Number: NCT01304316

Locations: 🇺🇸
University of Pennsylvania, School of Dental Medicine, Philadelphia, Pennsylvania, United States

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