NATIONAL INSTITUTES OF HEALTH

Tecovirimat did not improve clade I mpox resolution in DRC, but showed safe use and lower mortality. Ongoing trials like PALM007 and STOMP aim to develop effective mpox interventions.

New imaging method detects Aspergillus fumigatus fungal infections sooner using radioactive cellobiose and PET scans, aiding early diagnosis and treatment response monitoring in immunocompromised patients.

Tecovirimat, an antiviral, did not improve mpox lesion resolution in DRC's clade I mpox cases but was safe. The study showed lower mortality with high-quality care. Research continues for effective mpox treatments, emphasizing the need for trials in endemic settings like DRC.

Tecovirimat did not reduce mpox lesion duration in a DRC trial but showed lower mortality, highlighting the importance of supportive care. The study, part of the PALM007 trial, underscores the need for further mpox treatment research. Tecovirimat was well-tolerated, with ongoing studies like STOMP and UNITY exploring its efficacy against different mpox clades.

First patients enrolled in US pivotal study of AI-based image analysis module for lung cancer by Invenio Imaging, in collaboration with Johnson & Johnson and multiple cancer centers.

RCTs are largely white and male, with systemic biases affecting inclusion of marginalized groups. Researchers suggest changes in study design, recruitment, and reporting standards to address these issues.

The article highlights the evolution and current state of the biotechnology industry, emphasizing the U.S.'s leadership in biotech innovation and the emerging competition from China. It discusses China's strategic shift towards biotech innovation, supported by government policies, financial incentives, and the establishment of biotech clusters. The article also explores the challenges China faces in commercializing scientific discoveries and the importance of building a comprehensive biotech ecosystem to enhance commercialization capabilities.

The Dog Aging Project (DAP), a $23M study by CSU and other institutions, seeks dogs to understand aging. It studies genetics, healthspan, and conducts a rapamycin trial. Owners can nominate dogs at DogAgingProject.org, contributing to research on extending dogs' healthy lives.