Daiichi Sankyo Co., Ltd.

Novel Bacterial Consortium AUN Achieves Tumor Eradication Without Immune System Dependence

- Researchers at JAIST, Daiichi Sankyo, and University of Tsukuba developed AUN, a revolutionary bacterial cancer therapy that eliminates tumors without requiring immune cell function. - The therapy combines Proteus mirabilis and Rhodopseudomonas palustris bacteria that work synergistically to destroy tumor vasculature and cancer cells while minimizing side effects. - AUN represents a paradigm shift for immunocompromised cancer patients who cannot benefit from conventional immunotherapies, with clinical trials planned within six years.