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National Heart, Lung, and Blood Institute

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Healing Within: Mindfulness Smoking Cessation Intervention

Not Applicable

Recruiting

Conditions: Smoking Cessation

First Posted Date: 2025-06-10

Last Posted Date: 2025-06-10

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 48

Registration Number: NCT07013968

Locations: 🇺🇸
Black Hills Center for American Indian Health, Rapid City, South Dakota, United States

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies

Phase 1

Not yet recruiting

Conditions: Lung Transplantation

Interventions: Drug: fostamatinib
Drug: Placebo

First Posted Date: 2025-04-29

Last Posted Date: 2025-07-03

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 30

Registration Number: NCT06948097

Locations: 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
🇺🇸
National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, United States
🇺🇸
University of Utah Health, Salt Lake City, Utah, United States

and more 2 locations

VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) Catheters

Not Applicable

Not yet recruiting

Conditions: Ventricular Arrhythmia

First Posted Date: 2025-04-23

Last Posted Date: 2025-07-03

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 30

Registration Number: NCT06940752

Locations: 🇺🇸
Emory University, Atlanta, Georgia, United States

Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological Involvement

Phase 2

Recruiting

Conditions: Kohlmeier-Degos Disease
Malignant Atrophic Papulosis
Degos Disease
Papulosis, Malignant Atrophic

Interventions: Drug: Baricitinib

First Posted Date: 2025-04-11

Last Posted Date: 2025-07-03

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 12

Registration Number: NCT06923072

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions

Recruiting

Conditions: Dyslipidemia
Atherosclerosis

First Posted Date: 2024-11-06

Last Posted Date: 2025-05-31

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 1500

Registration Number: NCT06676046

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Epcoritamab in Chronic Lymphocytic Leukemia and Richter Syndrome

Phase 1

Recruiting

Conditions: Leukemia, Chronic Lymphocytic
Richter Syndrome

Interventions: Drug: epcoritamab

First Posted Date: 2024-11-06

Last Posted Date: 2025-07-03

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 30

Registration Number: NCT06676033

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

OurSleepKit to Support CPAP Adherence

Not Applicable

Recruiting

Conditions: Obstructive Sleep Apnea
CPAP Treatment
Treatment Adherence

Interventions: Behavioral: OurSleepKit

First Posted Date: 2024-10-01

Last Posted Date: 2025-02-14

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 360

Registration Number: NCT06621511

Locations: 🇺🇸
Northeastern University, Boston, Massachusetts, United States
🇺🇸
Northeastern University, Boston, Massachusetts, United States
🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States

and more 1 locations

Human Milk Oligosaccharide-Based Synbiotic Supplement for Intestinal Microbiota Dysbiosis

Early Phase 1

Recruiting

Conditions: Healthy Volunteers

Interventions: Dietary Supplement: Cardiosyn

First Posted Date: 2024-09-27

Last Posted Date: 2025-07-02

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 100

Registration Number: NCT06615986

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Thrombosis and Inflammation in Vessels Initiative (TIVI)

Recruiting

Conditions: Vascular Diseases
Cardiovascular Diseases

First Posted Date: 2024-08-14

Last Posted Date: 2025-06-27

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 1000

Registration Number: NCT06552767

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study

Not Applicable

Not yet recruiting

Conditions: Tricuspid Valve Insufficiency

Interventions: Device: TRAIPTA (Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty)

First Posted Date: 2024-06-28

Last Posted Date: 2025-07-03

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 60

Registration Number: NCT06479824

Locations: 🇺🇸
Medstar WHC, Washington, District of Columbia, United States
🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸
St. Francis Hospital and Heart Center, Roslyn, New York, United States

and more 1 locations

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