FDA Approves HemiClor: First Low-Dose Chlorthalidone Tablet for Hypertension Management
The FDA has approved HemiClor (12.5 mg chlorthalidone), the first low-dose formulation of this thiazide-like diuretic available in the U.S. for treating hypertension in adults.
Tonsil Removal Reduces Healthcare Needs in Children with Mild Sleep-Disordered Breathing
A new clinical trial shows adenotonsillectomy in children with mild sleep-disordered breathing reduces doctor visits by 32% and medication use by 48% within the first year after surgery.
NIH Funding Critical for Addressing Gaps in Pediatric Clinical Trials, Study Reveals
A comprehensive analysis of 4,527 clinical trials from 2015-2020 reveals that less than half of trials, whether NIH or industry-funded, focus on the top 20 childhood disease categories.
NIH-Funded BEST-ICU Trial Explores Behavioral Economics to Enhance Critical Care Bundle Implementation
The BEST-ICU trial, funded by NIH Collaboratory and NHLBI, investigates behavioral economics-based strategies to improve adoption of the evidence-based ABCDEF bundle in intensive care units.
IVOS Medical Secures $1.9M NIH Grant for BOSS G4 Video Laryngoscope Development
IVOS Medical has been awarded a $1.9M Phase II SBIR grant from the NIH to advance its IVOS BOSS G4 video laryngoscope, designed for improved airway management.
Fostamatinib Fails to Improve COVID-19 Recovery in Hospitalized Patients
A recent international trial found that fostamatinib, an immune-suppressing drug, did not significantly improve outcomes for hospitalized COVID-19 patients.
Nudge Trial: Text Message Reminders Fail to Improve Cardiovascular Medication Adherence
A pragmatic clinical trial, Nudge, found that text message reminders did not significantly improve cardiovascular medication adherence compared to usual care.
NIH Collaboratory Trials BEST-ICU and Chat 4 Heart Health Transition to Implementation Phase
The BEST-ICU trial, supported by the National Heart, Lung, and Blood Institute, is now in the implementation phase, focusing on improving care for critically ill adults by increasing ABCDEF bundle adoption.
Pomalidomide Shows Promise in Reducing Bleeding for Hereditary Hemorrhagic Telangiectasia
A Phase II clinical trial (PATH-HHT) demonstrated that pomalidomide significantly reduces the severity of nosebleeds in patients with hereditary hemorrhagic telangiectasia (HHT).
New Survey Reveals 12% of Americans Suffer from Chronic Insomnia as Sleep Health Concerns Rise
Recent nationwide survey by the American Academy of Sleep Medicine finds 12% of Americans are diagnosed with chronic insomnia, with highest prevalence among adults aged 25-44 years.