UNIVERSITY OF ROCHESTER

Nearly all pregnant women ingest the fungal toxin zearalenone, which mimics estrogen and may disrupt reproduction, according to a study by Rutgers and University of Rochester researchers. Zearalenone was detected in 97% of urine samples from pregnant women, with higher levels found in those consuming more ultraprocessed foods. The study suggests that reducing ultraprocessed food intake could minimize exposure.

Phase 3 trial results indicate nivolumab+AVD reduces side effects and disease progression risk by 50% in advanced Hodgkin lymphoma, paving way for pediatric access to checkpoint inhibitors.

Nivolumab (Opdivo) reduces side effects and disease progression risk by 50% compared to brentuximab vedotin (Adcetris) in advanced Hodgkin lymphoma treatment, according to a phase 3 clinical trial published in The New England Journal of Medicine.

A new clinical trial shows nivolumab, combined with three chemotherapies, significantly improves two-year progression-free survival rates to 92% in advanced Hodgkin lymphoma patients, including those as young as 12.

Technological advancements, including supercomputers and quantum computing, are poised to revolutionize drug discovery and clinical trials by exponentially increasing data processing capabilities. These innovations aim to address the complexities and data demands of modern clinical trials, ultimately speeding up the drug development process and bringing new treatments to market faster.

New funding from FDA enables researchers to use wearable sensors for early detection of Huntington's disease signs, focusing on gait and chorea. Led by University of Rochester’s Center for Health + Technology, the study aims to validate digital measures crucial for clinical trial outcomes, potentially impacting other neurological diseases like Parkinson's.

A global study confirms breast milk antibodies protect babies, with high levels linked to fending off rotavirus. Moms in lower-income nations had higher protective antibodies, while overweight/obese women had lower levels. Funded by the Bill and Melinda Gates Foundation, the study was published in the Journal of Clinical Investigation.