St. Jude Children's Research Hospital

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1962-01-01

Employees: -

Market Cap: -

Website: http://www.stjude.org/

Clinical Trials

A Severity-Adapted Clinical Trial of Diminished Bone Mineral Density in Acute Lymphoblastic Leukemia Survivors

Phase 3

Completed

Conditions: Leukemia, Lymphoblastic, Acute
Osteoporosis

Interventions: Other: Placebo
Drug: Calcium carbonate (Tums), vitamin D

First Posted Date: 2005-09-16

Last Posted Date: 2017-05-10

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 429

Registration Number: NCT00186901

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
🇺🇸
Preventive Medicine, University of Tennessee, Memphis, Tennessee, United States
🇺🇸
Metabolic Bone Center at the University of Tennessee, Memphis, Tennessee, United States

Marrow Mesenchymal Cell Therapy for Osteogenesis Imperfecta: A Pilot Study

Not Applicable

Completed

Conditions: Osteogenesis Imperfecta

First Posted Date: 2005-09-16

Last Posted Date: 2015-03-04

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 9

Registration Number: NCT00187018

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma

Phase 3

Active, not recruiting

Conditions: Retinal Neoplasm
Retinoblastoma

Interventions: Procedure: Enucleation
Drug: Vincristine, Carboplatin
Radiation: External Beam Radiation
Procedure: Focal Therapies
Drug: vincristine, cyclophosphamide, and doxorubicin
Drug: Vincristine, Carboplatin and Etoposide
Drug: Vincristine and Topotecan
Drug: Vincristine + Carboplatin + Etoposide
Procedure: Periocular carboplatin
Other: G-CSF

First Posted Date: 2005-09-16

Last Posted Date: 2024-10-09

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 107

Registration Number: NCT00186888

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Haploidentical Hematopoietic Stem Cell Transplantation Patients With Wiskott-Aldrich Syndrome

Phase 1

Completed

Conditions: Wiskott-Aldrich Syndrome

Interventions: Procedure: Hematopoietic stem cell transplantation
Device: Miltenyi CliniMACS selection system
Drug: Fludarabine, Melphalan, Thiotepa

First Posted Date: 2005-09-12

Last Posted Date: 2017-04-26

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 4

Registration Number: NCT00160355

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome

Phase 1

Completed

Conditions: Severe Combined Immunodeficiency

First Posted Date: 2005-09-09

Last Posted Date: 2009-05-20

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 4

Registration Number: NCT00152100

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Stem Cell Transplantation for Patients With Hematologic Malignancies

Phase 3

Completed

Conditions: Acute Lymphoblastic Leukemias
Acute Myelocytic Leukemia
Chronic Myeloid Leukemia
Juvenile Myelomonocytic Leukemia
Myelodysplastic Syndrome
Hemoglobinuria, Paroxysmal
Non-Hodgkin Lymphoma

Interventions: Procedure: Allogeneic Stem Cell Transplantation
Drug: Chemotherapy and antibodies

First Posted Date: 2005-09-09

Last Posted Date: 2009-01-29

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 33

Registration Number: NCT00152139

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and Lymphomas

Not Applicable

Completed

Conditions: Wilms Tumor
Neuroblastoma
Central Nervous System Tumors
Lymphomas

Interventions: Procedure: Stem Cell Transplantation
Drug: Busulfan, Melphalan

First Posted Date: 2005-09-09

Last Posted Date: 2009-02-13

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 26

Registration Number: NCT00152126

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound

Phase 1

Completed

Conditions: Sickle Cell Disease

Interventions: Procedure: Hematopoietic Stem Cell Transplantation
Device: CliniMACS
Drug: See intervention description

First Posted Date: 2005-09-09

Last Posted Date: 2017-04-26

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 5

Registration Number: NCT00152113

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Therapy for Pediatric Hodgkin Lymphoma

Phase 2

Completed

Conditions: Hodgkin Lymphoma

Interventions: Drug: 12 Week Stanford V Chemotherapy
Drug: 4 cycles of VAMP chemotherapy
Drug: 2 alternating cycles of VAMP/COP chemotherapy
Drug: 3 alternating cycles of VAMP/COP chemotherapy

First Posted Date: 2005-09-05

Last Posted Date: 2022-10-20

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 296

Registration Number: NCT00145600

Locations: 🇺🇸
Dana Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸
Stanford University, Palo Alto, California, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

and more 2 locations

Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies

Phase 2

Completed

Conditions: Acute Lymphoblastic Leukemia (ALL)
Acute Myeloid Leukemia (AML)
Secondary AML
Myelodysplastic Syndrome (MDS)
Secondary MDS
Chronic Myeloid Leukemia
Juvenile Myelomonocytic Leukemia (JMML)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Lymphoma, Non-Hodgkin
Hodgkin Disease

Interventions: Procedure: Stem Cell Transplantation
Device: Miltenyi Biotec CliniMACS
Drug: Systemic chemotherapy and antibodies

First Posted Date: 2005-09-05

Last Posted Date: 2009-02-13

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 25

Registration Number: NCT00145613

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

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