LOUGHBOROUGH UNIVERSITY

Rejuvenate Biomed Partners with NIHR Leicester BRC for Phase 2 Trial of Novel COPD-Related Sarcopenia Treatment

7 months ago

• Rejuvenate Biomed, University of Leicester, NIHR Leicester BRC, and Wellcome Leap have partnered to conduct a Phase 2 clinical trial evaluating RJx-01 for COPD-related sarcopenia, with patient enrollment expected to begin in the first half of 2025. • The double-blind placebo-controlled trial will assess RJx-01's safety and efficacy in 130 older individuals hospitalized with severe acute COPD exacerbations, focusing on maintaining muscle integrity and improving physical function. • RJx-01 previously demonstrated promising results in a Phase 1b trial, showing meaningful improvements in muscle strength, function, and fatigue resistance in people with disuse-induced muscle weakness.