SOCIEDADE BENEF ISRAELITABRAS HOSPITAL ALBERT EINSTEIN

Tele-ICU Intervention Fails to Improve Outcomes in Critically Ill Patients: TELESCOPE Trial

7 months ago

• A large cluster randomized trial (TELESCOPE) across 30 Brazilian ICUs evaluated the impact of tele-ICU on critically ill patients. • The tele-ICU intervention included multidisciplinary rounds led by remote intensivists, monthly audit meetings, and evidence-based protocols. • The study found no significant reduction in ICU length of stay or in-hospital mortality with the tele-ICU intervention compared to usual care. • The findings suggest that the effectiveness of tele-ICU is context-specific and requires customization based on local needs and resources.

Real-world Outcomes of Advanced Renal Cell Carcinoma Treatment with Immune-oncology Combinations

a year ago

A retrospective study involving 930 patients from 58 centers across 20 countries evaluated the effectiveness of immune-oncology combinations in treating advanced renal cell carcinoma (RCC). The study found that intermediate-risk patients benefited more from a combination of immunotherapy and antiangiogenic therapy (IO + TKI) compared to double immunotherapy (IO + IO), showing longer progression-free survival (PFS) and overall survival (OS). However, no significant difference was observed in poor-risk patients between the two treatment strategies.