GILEAD SCIENCES SL

🇪🇸Spain
Ownership
-
Established
1994-01-01
Employees
-
Market Cap
$95.8B
Website
http://www.gilead.com/about/worldwide-operations/europe/spain
biopharmadive.com
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Darzalex in smoldering myeloma, Merck's ADC data and Novo's sickle cell drug

Darzalex reduced smoldering multiple myeloma progression risk by 51%; BEAM-101 increased fetal hemoglobin in sickle cell patients; zilovertamab vedotin achieved complete responses in lymphoma; etavopivat halved sickle cell pain crises; anito-cel showed strong response in multiple myeloma, with potential to surpass existing therapies.
gilead.com
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Kite Presents New Data Underscoring Curative Potential of Yescarta® in Relapsed

Kite, a Gilead Company, announced findings from three new Yescarta analyses at the 66th ASH Annual Meeting, demonstrating improved outcomes for R/R LBCL patients. The largest RWE analysis showed a 71% OS rate in second-line treatment, consistent with ZUMA-7 outcomes. RWE also indicated a decreasing trend in CRS and ICANS incidence and severity over time in the third-line-plus setting. The ALYCANTE study revealed stable long-term HRQoL for R/R LBCL patients treated with Yescarta.
openpr.com
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Oncology Market Overview and Leading Players: Daiichi Sankyo

The Oncology Market is critical in global healthcare, driven by cancer prevalence, technological advancements, and strategic collaborations. Key players like Daiichi Sankyo, Bayer AG, and others innovate in diagnostics, treatments, and precision medicine. Market growth is fueled by R&D investments, sustainability focus, and consumer awareness. Challenges include regulatory constraints and talent shortages. Technological integrations like AI and IoT enhance patient care and operational efficiency.
genengnews.com
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ARK Mostly Bullish on CRISPR Therapeutics

CRISPR Therapeutics' stock has declined 46% since its 52-week high, despite FDA approval of Casgevy for sickle cell disease and beta thalassemia. Analysts suggest patient uptake has been slower than expected, partly due to treatment alternatives and high cost. ARK Investment Management has increased its stake in CRISPR Therapeutics, believing in the long-term value of gene editing cures. Despite recent dips, ARK funds have sold off shares, reflecting broader investor sentiment. Casgevy's commercial progress is seen as positive, with 45 of 75 treatment centers activated and initial revenue generated.
medpagetoday.com
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JAK Inhibitor Comes Up Short in Phase III Crohn's Disease Trial

Filgotinib, an oral JAK inhibitor, met only one of four primary endpoints in a phase III Crohn's disease trial, possibly due to study design issues. Clinical remission was achieved by more patients previously treated with biologics, but endoscopic response was not met. Maintenance phase showed better results, with clinical and endoscopic remission rates improving. Study limitations included early endoscopic assessment and high placebo response rates.
globenewswire.com
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Chronic Pseudomonas Aeruginosa Pulmonary Infections Pipeline Insight 2024

The 'Chronic Pseudomonas Aeruginosa Pulmonary Infections - Pipeline Insight, 2024' report by ResearchAndMarkets.com covers 10+ companies and 12+ pipeline drugs, including clinical and nonclinical stage products, with a focus on therapeutics assessment by product type, stage, route of administration, and molecule type. Key drugs include Armata Pharmaceuticals' AP-PA02 in Phase II and BiomX's BX004 in Phase I/II.

Breaking New Ground in Immunology & Inflammation

Kathy Dong, PharmD, leads Electra Therapeutics, developing ELA026, a first-in-class monoclonal antibody targeting SIRP for sHLH, a rare, life-threatening hyperinflammatory disease. ELA026 showed promising clinical results, achieving a 100% response rate in mHLH patients, with 100% discharge and 90% 60-day survival, suggesting rapid suppression of hyperinflammation and potential as a transformative treatment.
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