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Boston Children's Hospital

πŸ‡ΊπŸ‡ΈUnited States
Ownership
-
Established
1869-01-01
Employees
-
Market Cap
-
Website
https://www.childrenshospital.org/

Clinical Trials

576

Active:37
Completed:269

Trial Phases

6 Phases

Early Phase 1:2
Phase 1:36
Phase 2:35
+3 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (365 trials with phase data)β€’ Click on a phase to view related trials

Not Applicable
251 (68.8%)
Phase 1
36 (9.9%)
Phase 2
35 (9.6%)
Phase 4
24 (6.6%)
Phase 3
17 (4.7%)
Early Phase 1
2 (0.5%)

Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

Not Applicable
Not yet recruiting
Conditions
Cowden's Disease
Cowden's Syndrome
Lhermitte-Duclos Disease
Cerebellum Dysplastic Gangliocytoma
Bannayan Zonana Syndrome
Myhre Riley Smith Syndrome
Riley Smith Syndrome
PTEN Hamartoma Tumor Syndrome
Bannayan Riley Ruvalcaba Syndrome
Interventions
Drug: Everolimus blinded oral capsules
Drug: Placebo
First Posted Date
2025-10-20
Last Posted Date
2025-10-20
Lead Sponsor
Boston Children's Hospital
Target Recruit Count
60
Registration Number
NCT07218575

Dietary Intervention Using a Gluten-free App to Improve Tracking, Adherence, and Learning(DIGITAL) Study

Not Applicable
Not yet recruiting
Conditions
Celiac Disease in Children
First Posted Date
2025-09-25
Last Posted Date
2025-09-29
Lead Sponsor
Boston Children's Hospital
Target Recruit Count
120
Registration Number
NCT07192874

Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient

Not yet recruiting
Conditions
Tetrology of Fallot
First Posted Date
2025-09-19
Last Posted Date
2025-09-19
Lead Sponsor
Boston Children's Hospital
Target Recruit Count
40
Registration Number
NCT07184476

Exercise as Medicine for Pediatric Chronic Pain

Not Applicable
Not yet recruiting
Conditions
Chronic Pain
Adolescent
Child
First Posted Date
2025-09-19
Last Posted Date
2025-09-19
Lead Sponsor
Boston Children's Hospital
Target Recruit Count
66
Registration Number
NCT07182006
Locations
πŸ‡ΊπŸ‡Έ

Boston Children's Hospital at 2 Brookline Place, Brookline, Massachusetts, United States

Genetics of Neonatal Encephalopathy and Related Disorders

Not yet recruiting
Conditions
Neonatal Encephalopathy
Hypoxic Ischaemic Encephalopathy (HIE)
First Posted Date
2025-09-10
Last Posted Date
2025-09-10
Lead Sponsor
Boston Children's Hospital
Target Recruit Count
300
Registration Number
NCT07165938
Locations
πŸ‡ΊπŸ‡Έ

Boston Children's Hospital, Boston, Massachusetts, United States

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News

Ovid Therapeutics' OV329 Shows 53% GABA Inhibition in Phase 1 Trial for Drug-Resistant Epilepsy

Ovid Therapeutics announced positive Phase 1 results for OV329, a next-generation GABA-aminotransferase inhibitor, showing 53% inhibition of GABA-AT at 5 mg dose with statistical significance (p=0.0001).

Apertura Gene Therapy Licenses Blood-Brain Barrier-Penetrant AAV Capsid to Multiple Partners for CNS Treatments

Apertura Gene Therapy has licensed its novel TfR1 CapX capsid technology to Galibra Neuroscience and Emugen Therapeutics for central nervous system gene therapy programs.

Insulin Access Disparities Persist Despite Cost Stabilization, Study Reveals Long-Term Health System Burden

A comprehensive analysis of insulin out-of-pocket costs and usage patterns from 2008-2021 reveals persistent disparities in insulin access between higher-income and lower-income patients with diabetes.

Dana-Farber, Boston Children's Hospital, and Broad Clinical Labs Launch BrightSeq Initiative for Pediatric Cancer Genomics

Dana-Farber Cancer Institute, Boston Children's Hospital, and Broad Clinical Labs have formed BrightSeq, a collaborative initiative to develop clinical molecular testing assays specifically for pediatric cancers.

First Commercial Brain Gene Therapy Treatments Delivered in US Using ClearPoint Neuro's SmartFlow Cannula

The first commercial gene therapy treatments ever delivered directly to the brain in the United States have been successfully performed using ClearPoint Neuro's SmartFlow Neuro Cannula to administer KEBILIDI for AADC deficiency.

NS Pharma and Boston Children's Hospital Form Strategic Alliance to Advance Rare Disease Therapies

NS Pharma's parent company Nippon Shinyaku has finalized a strategic partnership with Boston Children's Hospital to develop innovative therapies for rare diseases.

Psilocybin Clinical Trial Targets Treatment-Resistant IBS in Groundbreaking Gastroenterology Study

Dr. Erin E. Mauney at Massachusetts General Hospital is conducting the first clinical trial examining psilocybin's effects on treatment-resistant irritable bowel syndrome (IBS).

Dupilumab Reduces Asthma Exacerbations in Children Regardless of Disease Duration

Children with uncontrolled moderate to severe asthma experienced significantly fewer exacerbations when treated with dupilumab compared to placebo, regardless of how long they had been living with the disease.

FDA Clears BlackfinBio's Novel Gene Therapy Trial for Rare Childhood Neurological Disease SPG47

The FDA has cleared BlackfinBio's IND application to begin a Phase 1/2 clinical trial of BFB-101, a gene therapy designed to treat Hereditary Spastic Paraplegia Type 47 (SPG47), a rare neurological disorder with no existing treatments.

FDA Expands Luminopia's Digital Therapeutic Approval for Amblyopia Treatment to Children Aged 8-12

Luminopia's VR-based digital therapeutic for amblyopia has received FDA clearance for children aged 8-12 years, expanding from its previous 4-7 year age indication based on robust real-world evidence.

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