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HELLENIC INSTITUTE FOR THE STUDY OF SEPSIS

🇬🇷Greece
Ownership
Private
Employees
-
Market Cap
-
Website

STS Administration on Coronavirus Disease (COVID-19) Patients in Critical Care

Phase 2
Recruiting
Conditions
COVID-19
Virus Diseases
Corona Virus Infection
Interventions
Drug: Sodium Thiosulfate 25% Solution for Injection
First Posted Date
2022-03-14
Last Posted Date
2023-01-13
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
30
Registration Number
NCT05277285
Locations
🇬🇷

General Hospitan of Athens KAT 2nd Department of ICU, Athens, Kifisia, Greece

Personalized Immunotherapy in Sepsis

Phase 2
Completed
Conditions
Sepsis
Interventions
First Posted Date
2021-08-04
Last Posted Date
2025-03-19
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
280
Registration Number
NCT04990232
Locations
🇮🇹

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

🇩🇪

Intensive Care Unit, Jena University Hospital, Jena, Germany

🇬🇷

2nd Department of Critical Care Medicine, ATTIKON University Hospital, Athens, Haidari, Greece

and more 32 locations

Addressing Personalized Needs in Clostridioides Difficile Infection

Not Applicable
Completed
Conditions
Clostridioides Difficile Infection
Interventions
Diagnostic Test: Microbiome analysis
First Posted Date
2021-01-26
Last Posted Date
2023-12-12
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
153
Registration Number
NCT04725123
Locations
🇬🇷

4th Department of Internal Medicine, ATTIKON University General Hospital, Athens, Greece

Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia

Phase 3
Completed
Conditions
Mortality
SIRS
Community-acquired Pneumonia
Inflammatory Response
Biomarkers
Sepsis
Interventions
First Posted Date
2021-01-26
Last Posted Date
2023-12-12
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
278
Registration Number
NCT04724044
Locations
🇬🇷

Department of Internal Medicine, Larissa University General Hospital, Larissa, Greece

🇬🇷

4th Department of Internal Medicine, Attikon University Hospital, Athens, Greece

🇬🇷

1st Department of Internal Medicine, Konstantopouleio-Patission General Hospital, Athens, Greece

and more 15 locations

suPAR-Guided Anakinra Treatment for Management of Severe Respiratory Failure by COVID-19

Phase 3
Completed
Conditions
Covid19
Interventions
Drug: Placebo
First Posted Date
2020-12-23
Last Posted Date
2022-09-06
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
606
Registration Number
NCT04680949
Locations
🇬🇷

1st Department of Internal Medicine, General Hospital of Voula ASKLEPIEIO, Athens, Greece

🇬🇷

1st University Department of Internal Medicine, General Hospital of Athens LAIKO, Athens, Greece

🇬🇷

3rd Department of Internal Medicine, General Hospital of Athens KORGIALENEIO-BENAKEIO E.E.S., Athens, Greece

and more 37 locations

Bacillus Calmette-guérin Vaccination to Prevent COVID-19

Phase 4
Completed
Conditions
COVID-19
Corona Virus Infection
Coronary Heart Disease
Chronic Obstructive Pulmonary Disease
Virus Diseases
Interventions
Biological: Placebo
Biological: BCG vaccine
First Posted Date
2020-06-04
Last Posted Date
2021-05-11
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
301
Registration Number
NCT04414267
Locations
🇬🇷

Department of Therapeutics, Alexandra General Hospital, Athens, Greece

🇬🇷

Department of Internal Medicine, Patras University Hospital, Patras, Greece

🇬🇷

3rd University Department of Internal Medicine, General Hospital of Chest Diseases of Athens I SOTIRIA, Athens, Greece

and more 12 locations

Anti-inflammatory Clarithromycin for Improving COVID-19 Infection Early

Phase 2
Completed
Conditions
COVID-19
Virus Diseases
Corona Virus Infection
Interventions
First Posted Date
2020-05-21
Last Posted Date
2021-01-11
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
90
Registration Number
NCT04398004
Locations
🇬🇷

2nd University Department of Internal Medicine, IPPOKRATEION General Hospital of Athens, Athens, Greece

🇬🇷

1st Department of Internal Medicine, General University Hospital of Ioannina, Ioánnina, Greece

🇬🇷

COVID-19 Department, General Hospital of Attica SISMANOGLEIO-AMALIA FLEMING, Marousi, Athens, Greece

and more 6 locations

suPAR-guided Anakinra Treatment for Validation of the Risk and Management of Respiratory Failure by COVID-19 (SAVE)

Phase 2
Completed
Conditions
Corona Virus Infection
COVID-19
Virus Diseases
Lower Respiratory Tract Infection Viral
Interventions
First Posted Date
2020-04-22
Last Posted Date
2023-07-13
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
1000
Registration Number
NCT04357366
Locations
🇬🇷

Department of Internal Medicine, University General Hospital of Larissa, Larissa, Greece

🇬🇷

2nd Department of Internal Medicine, General Hospital of Piraeus TZANEIO, Piraeus, Greece

🇬🇷

COVID-19 Department, General Hospital of Attica SISMANOGLEIO-AMALIA FLEMING, Marousi, Athens, Greece

and more 25 locations

Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction

Phase 2
Completed
Conditions
COVID-19
Virus Diseases
Macrophage Activation Syndrome
Corona Virus Infection
Interventions
First Posted Date
2020-04-09
Last Posted Date
2021-01-11
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
102
Registration Number
NCT04339712
Locations
🇬🇷

Intensive Care Unit, Ioannina University Hospital, Ioánnina, Ioannina, Greece

🇬🇷

Department of Internal Medicine, Patras University Hospital, Patras, Rion, Greece

🇬🇷

Intensive Care Unit, "Latsio", Thriasio Elefsis General Hospital, Elefsína, Greece

and more 14 locations

Incretin Hormones in Type 1 Diabetes Mellitus;Effect of Metformin Treatment

Phase 3
Conditions
Type 1 Diabetes Mellitus
Interventions
Drug: Placebo
First Posted Date
2019-11-26
Last Posted Date
2020-02-18
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
44
Registration Number
NCT04177303
Locations
🇬🇷

Diabetes Center, 1st Internal Medicine Department, AHEPA University General Hospital of Thessaloniki, Thessaloníki, Thessaloniki, Greece

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