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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria

Phase 2
Completed
Conditions
Diabetic Nephropathy
Type 2 Diabetes Mellitus
Interventions
Drug: Placebo
Drug: CCX140-B
First Posted Date
2011-09-26
Last Posted Date
2025-02-27
Lead Sponsor
Amgen
Target Recruit Count
20
Registration Number
NCT01440257
Locations
🇳🇱

Centre for Human Drug Research, Leiden, Netherlands

Safety & Tolerability of Cinacalcet in Pediatric Patients With Chronic Kidney Disease and Secondary Hyperparathyroidism

Phase 2
Terminated
Conditions
Hyperparathyroidism, Secondary
Chronic Kidney Disease
Interventions
Drug: Standard of Care
First Posted Date
2011-09-23
Last Posted Date
2020-06-17
Lead Sponsor
Amgen
Target Recruit Count
18
Registration Number
NCT01439867
Locations
🇸🇰

Research Site, Kosice, Slovakia

Open Label Study of Long Term Evaluation Against LDL-C Trial

Phase 2
Completed
Conditions
Hypercholesterolemia
Interventions
Biological: Evolocumab
Other: Standard of care
First Posted Date
2011-09-23
Last Posted Date
2022-09-21
Lead Sponsor
Amgen
Target Recruit Count
1324
Registration Number
NCT01439880
Locations
🇬🇧

Research Site, London, United Kingdom

Study to Evaluate Darbepoetin Alfa in Pediatric Subjects With Anemia Due to Chronic Kidney Disease

Phase 1
Withdrawn
Conditions
Anemia
Chronic Kidney Disease
Interventions
First Posted Date
2011-09-02
Last Posted Date
2016-06-17
Lead Sponsor
Amgen
Registration Number
NCT01428154

Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer

Phase 3
Completed
Conditions
Bone Metastases in Men With Hormone-Refractory Prostate Cancer
Bone Metastases in Subjects With Advanced Breast Cancer
Interventions
First Posted Date
2011-08-18
Last Posted Date
2019-09-24
Lead Sponsor
Amgen
Target Recruit Count
129
Registration Number
NCT01419717
Locations
🇺🇦

Research Site, Lviv, Ukraine

Open-label Study of the Safety and Activity of Oprozomib in Patients With Hematologic Malignancies

Phase 1
Terminated
Conditions
Multiple Myeloma
Waldenstrom Macroglobulinemia
Interventions
First Posted Date
2011-08-15
Last Posted Date
2022-11-08
Lead Sponsor
Amgen
Target Recruit Count
210
Registration Number
NCT01416428
Locations
🇺🇸

Mayo Clinic Scottsdale, Scottsdale, Arizona, United States

🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

🇺🇸

Pacific Cancer Care, Salinas, California, United States

and more 15 locations

Comparison of Survival Benefit of Panitumumab With Supportive Care to Best Supportive Care Alone in Patients With Metastatic Colorectal Cancer

Phase 3
Completed
Conditions
Metastatic Colorectal Cancer
Interventions
Other: Best Supportive Care (BSC)
First Posted Date
2011-08-09
Last Posted Date
2017-03-15
Lead Sponsor
Amgen
Target Recruit Count
377
Registration Number
NCT01412957
Locations
🇷🇸

Research Site, Sremska Kamenica, Serbia

Carfilzomib Multiple Myeloma Expanded Access Protocol for Patients With Relapsed and Refractory Disease

Conditions
Multiple Myeloma
First Posted Date
2011-08-05
Last Posted Date
2017-05-02
Lead Sponsor
Amgen
Registration Number
NCT01410500

Double-blind, Multiple Dose Study of Tezepelumab (AMG 157) in Adults With Mild Atopic Asthma

Phase 1
Completed
Conditions
Asthma
Interventions
Drug: Placebo
Biological: Tezepelumab
First Posted Date
2011-07-29
Last Posted Date
2022-10-17
Lead Sponsor
Amgen
Target Recruit Count
31
Registration Number
NCT01405963
Locations
🇨🇦

Research Site, Saskatoon, Saskatchewan, Canada

Safety, Tolerability, and Pharmacokinetics of AMG 827 in Adolescents With Asthma

Phase 1
Withdrawn
Conditions
Asthma
Interventions
Drug: AMG 827 or Placebo
First Posted Date
2011-07-15
Last Posted Date
2013-11-25
Lead Sponsor
Amgen
Registration Number
NCT01395485
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