HIV VACCINE TRIALS NETWORK
Safety and Immunogenicity of MRNAs Encoding HIV Immunogens (eOD-GT8 60mer, Core-g28v2 60mer, N332-GT5 Gp151) in Adult Participants Without HIV and in Overall Good Health in South Africa (HVTN 317)
- Conditions
- Interventions
- First Posted Date
- 2024-11-19
- Last Posted Date
- 2024-11-19
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 96
- Registration Number
- NCT06694753
- Locations
- 🇿🇦
Setshaba Research Centre CRS, Soshanguve, Gauteng, South Africa
🇿🇦Soweto HVTN CRS, Soweto, Gauteng, South Africa
🇿🇦Chatsworth CRS, Chatsworth, Kwa Zulu Natal, South Africa
Comparing the Safety and Immunogenicity of 426c.Mod.Core-C4b Vaccine Adjuvanted with 3M-052-AF + Alum in Infants with Perinatal HIV Exposure Who Are Without HIV At Birth
- Conditions
- Interventions
- First Posted Date
- 2024-09-26
- Last Posted Date
- 2024-09-26
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 22
- Registration Number
- NCT06613789
- Locations
- 🇿🇦
Soweto HVTN CRS, Soweto, Gauteng, South Africa
Evaluating the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibodies in Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2023-07-25
- Last Posted Date
- 2024-07-05
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 77
- Registration Number
- NCT05959707
- Locations
- 🇿🇦
Groote Schuur HIV CRS, Cape Town, Western Cape, South Africa
🇿🇦Klerksdorp CRS, Klerksdorp, South Africa
🇿🇦Ward 21 CRS, Johannesburg, South Africa
Evaluating the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South Africa
- Conditions
- Interventions
- First Posted Date
- 2023-07-17
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 276
- Registration Number
- NCT05947890
- Locations
- 🇿🇦
Cape Town - Khayelitsha, Cape Town, South Africa
🇿🇦Durban - Botha's Hill CRS, Durban, Kwa Zulu Natal, South Africa
🇿🇦Johannesburg - CHRU, Westdene, Gauteng,, South Africa
Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of HIV-1 Chimp Adenovirus Vaccines Expressing Clade C gp140 & CH505TF gp120 Protein Boost in HIV-uninfected Adult.
- Conditions
- Interventions
- First Posted Date
- 2022-01-10
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 34
- Registration Number
- NCT05182125
- Locations
- 🇿🇦
CAPRISA eThekwini CRS, Durban, South Africa
🇿🇦Emavundleni CRS, Cape Town, South Africa
🇿🇦Setshaba Research Centre CRS, Soshanguve, South Africa
Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study
- Conditions
- Interventions
- First Posted Date
- 2021-04-26
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 13
- Registration Number
- NCT04860323
- Locations
- 🇲🇼
Blantyre CRS, Blantyre, Malawi
🇿🇦CAPRISA eThekwini CRS, Durban, South Africa
🇿🇼Seke South CRS, Harare, Zimbabwe
Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 704/HPTN 085 AMP Study
- First Posted Date
- 2021-03-17
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 18
- Registration Number
- NCT04801758
- Locations
- 🇵🇪
Asociacion Civil Selva Amazonica (ACSA), Iquitos CRS, Iquitos, Maynas, Peru
🇵🇪San Miguel CRS, Lima, Peru
🇵🇪Via Libra CRS, Lima, Peru
Evaluating Safety and Immune Response to the HIV-1 CH505 Transmitted/Founder gp120 Adjuvanted With GLA-SE in Healthy, HIV-exposed Uninfected Infants
- Conditions
- Interventions
- First Posted Date
- 2020-10-29
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 38
- Registration Number
- NCT04607408
- Locations
- 🇿🇦
Perinatal HIV Research Unit (PHRU), Soweto CRS, Johannesburg, Gauteng, South Africa
Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19
- First Posted Date
- 2020-05-27
- Last Posted Date
- 2022-05-27
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 759
- Registration Number
- NCT04403880
- Locations
- 🇿🇼
Zengeza CRS, Chitungwiza, Zimbabwe
🇺🇸University of Rochester Vaccines to Prevent HIV Infection CRS, Rochester, New York, United States
🇺🇸Columbia P&S CRS, New York, New York, United States
An Observational Study of Long-term Outcomes of HIV-1 Infection in Persons Who Become HIV-1 Infected After Enrollment in HIV-1 Vaccine Trials
- First Posted Date
- 2017-11-09
- Last Posted Date
- 2022-04-18
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 209
- Registration Number
- NCT03337906
- Locations
- 🇺🇸
UIC Project WISH CRS, Chicago, Illinois, United States
🇺🇸The Hope Clinic of the Emory Vaccine Center CRS, Decatur, Georgia, United States
🇺🇸Brigham and Women's Hospital Vaccine CRS (BWH VCRS), Boston, Massachusetts, United States