Biomerica Appoints Scott Madel as Chief Commercial Officer to Drive inFoods IBS Test Commercialization
Biomerica has appointed Scott Madel as Chief Commercial Officer to accelerate commercialization of its inFoods IBS diagnostic test, bringing over 20 years of experience in laboratory testing and clinical diagnostics.
First Patient Treated with Novel B-Cell Targeting Therapy for Myasthenia Gravis in Phase III Trial
The first patient worldwide has been treated with Remibrutinib, a novel B-cell targeting therapy for Myasthenia Gravis, marking the start of an international Phase III clinical trial at HonorHealth Research Institute.
Protara Therapeutics Appoints William Conkling as Chief Commercial Officer to Lead Commercialization Strategy
Protara Therapeutics has appointed William Conkling as Chief Commercial Officer, bringing over two decades of experience in developing and commercializing cancer and rare disease therapeutics.
Schizophrenia Market Set for Strong Growth, Driven by Novel Therapies
• The schizophrenia market is expected to grow significantly, driven by the launch of novel therapies and increased diagnosis rates. • Long-acting injectables (LAIs) are gaining traction despite higher costs, offering an alternative to oral antipsychotics. • The US dominates the schizophrenia market due to a large patient population and high drug costs. • Emerging treatments like Cobenfy, evenamide, Ingrezza, and iclepertin aim to address unmet needs in managing both positive and negative symptoms.
Alpelisib Plus Fulvestrant Shows Promise in Advanced Breast Cancer With PIK3CA Mutation
Alpelisib combined with fulvestrant demonstrates notable activity in patients with PIK3CA-mutated, hormone receptor-positive, HER2-negative advanced breast cancer after CDK4/6 inhibitor and aromatase inhibitor failure.
Capmatinib Demonstrates Sustained Efficacy in MET Exon 14-Mutated NSCLC
• Final results from the phase II GEOMETRY mono-1 trial reinforce capmatinib's effectiveness in treating NSCLC patients with MET exon 14 skipping mutations. • In treatment-naive patients, capmatinib achieved a 68% objective response rate and a median overall survival of 21.4 months. • Previously treated patients experienced a 44% objective response rate and a median overall survival of 16.8 months with capmatinib. • The study confirms MET exon 14 skipping as a targetable oncogenic driver, supporting capmatinib as a viable treatment option.
Asciminib's Flexible Dosing: Daily Regimen Shows Comparable Efficacy and Safety in CML
Population pharmacokinetic and exposure-response analyses support the use of asciminib 80 mg once daily as an alternative to the 40 mg twice daily regimen for CML-CP patients without the T315I mutation.