MedPath

Commons, Marty

🇺🇸United States
Ownership
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Employees
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Market Cap
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Website

Study of Safety and Efficacy in Patients With Malignant Rhabdoid Tumors (MRT) and Neuroblastoma

Phase 1
Terminated
Conditions
Neuroblastoma
Malignant Rhabdoid Tumors (MRT)
Interventions
First Posted Date
2012-12-12
Last Posted Date
2019-11-22
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
32
Registration Number
NCT01747876
Locations
🇺🇸

Childrens Healthcare of Atlanta Dept of Oncology, Atlanta, Georgia, United States

🇺🇸

Dana Farber Cancer Institute SC-7, Boston, Massachusetts, United States

🇺🇸

Cincinnati Children's Hospital Medical Center Dept of Oncology, Cincinnati, Ohio, United States

and more 4 locations

A Study That Switched Patients From Imatinib to Nilotinib and Then Was Followed by Treatment Cessation

Phase 2
Completed
Conditions
CML
Interventions
First Posted Date
2012-12-07
Last Posted Date
2020-03-10
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
59
Registration Number
NCT01744665
Locations
🇺🇸

Compassionate Care Research Group Inc CCCMG, Fountain Valley, California, United States

🇺🇸

Michigan State University / Breslin Cancer Center Breslin Cancer Center (3), Lansing, Michigan, United States

🇺🇸

Hackensack University Medical Center John Theurer Cancer Center, Hackensack, New Jersey, United States

and more 51 locations

An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis

Phase 4
Completed
Conditions
Oestrogen Receptor Positive Advanced Breast Cancer
Interventions
First Posted Date
2012-12-06
Last Posted Date
2019-07-18
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
52
Registration Number
NCT01743560
Locations
🇬🇧

Novartis Investigative Site, Portsmouth, United Kingdom

A Randomized Phase III Study to Assess the Effect of a Longer Duration of Consolidation Treatment With Nilotinib on TFR in CP CML.

Phase 3
Completed
Conditions
Philadelphia Chromosome Positive (PH+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)
Interventions
First Posted Date
2012-12-06
Last Posted Date
2021-07-15
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
620
Registration Number
NCT01743989
Locations
🇬🇧

Novartis Investigative Site, London, United Kingdom

Compare the Effect of a Remote Monitoring System Using the EXACT Tool to Reduce Hospitalizations Due to Chronic Obstructive Pulmonary Disease (COPD) Exacerbations. EXACT = Exacerbations of Chronic Pulmonary Disease Tool.

Phase 1
Completed
Conditions
Remote Patient Monitoring in COPD Patients
Interventions
Device: Remote Patient Monitoring
Other: Usual care
First Posted Date
2012-12-06
Last Posted Date
2020-12-10
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
118
Registration Number
NCT01744028
Locations
🇸🇪

Novartis Investigative Site, Östersund, Sweden

Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator

Phase 4
Active, not recruiting
Conditions
GIST and CML
Interventions
First Posted Date
2012-12-05
Last Posted Date
2025-03-24
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
155
Registration Number
NCT01742299
Locations
🇺🇸

University of California LA, Los Angeles, California, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

Sidney Kimmel CCC At JH, Baltimore, Maryland, United States

and more 7 locations

Phase I Study of LDK378 in Pediatric, Malignancies With a Genetic Alteration in Anaplastic Lymphoma Kinase (ALK)

Phase 1
Completed
Conditions
ALK-activated Tumors
Interventions
First Posted Date
2012-12-05
Last Posted Date
2020-06-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
83
Registration Number
NCT01742286
Locations
🇺🇸

Dana Farber Cancer Institute Dept of Onc, Boston, Massachusetts, United States

🇺🇸

Memorial Sloan Kettering SC - 7, New York, New York, United States

🇬🇧

Novartis Investigative Site, Sutton, Surrey, United Kingdom

and more 3 locations

Study Efficacy and Safety of INC280 in Patients With Advanced Hepatocellular Carcinoma.

Phase 2
Terminated
Conditions
Advanced Hepatocellular Carcinoma With c-MET Dysregulation
Interventions
Drug: INC280
First Posted Date
2012-11-30
Last Posted Date
2023-07-06
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
38
Registration Number
NCT01737827
Locations
🇹🇭

Novartis Investigative Site, Bangkok, Thailand

An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study)

Phase 4
Completed
Conditions
Thalassemia, Non-transfusional-dependent Thalassemia (NTDT), Myeloplastic Dysplasia (MDS), Other Anemia
Interventions
Device: MRI scan
First Posted Date
2012-11-29
Last Posted Date
2017-04-12
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
243
Registration Number
NCT01736540
Locations
🇦🇺

Novartis Investigative Site, Perth, Western Australia, Australia

Study to Allow Access to Nilotinib for Patients Who Are on Nilotinib Treatment in a Novartis-sponsored Study

Phase 4
Completed
Conditions
Chronic Myelogenous Leukemia (CML)
Metastatic Gastrointestinal Stromal Tumors (GIST)
Acute Lymphoblastic Leukemia (ALL)
Receptor Tyrosine Kinase (KIT) Mutated Melanoma
Interventions
First Posted Date
2012-11-28
Last Posted Date
2024-02-08
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
57
Registration Number
NCT01735955
Locations
🇬🇧

Novartis Investigative Site, Newcastle upon Tyne, United Kingdom

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