MedPath

Commons, Marty

🇺🇸United States
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MAP to Provide Access to Ruxolitinib, for Patients With Polycythemia Vera

Conditions
Polycythemia Vera
First Posted Date
2022-03-08
Last Posted Date
2024-10-28
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT05269771

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Phase 2
Recruiting
Conditions
Lupus Nephritis
Interventions
Drug: Placebo + standard of care
Drug: Iptacopan (part 1)
Drug: Iptacopan (part 2)
Drug: Iptacopan + placebo
First Posted Date
2022-03-07
Last Posted Date
2024-05-30
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
240
Registration Number
NCT05268289
Locations
🇹🇷

Novartis Investigative Site, Talas / Kayseri, Turkey

Effectiveness of Brolucizumab in Pre-treated Patients With nAMD in the Real-world Setting

Recruiting
Conditions
Neovascular Age-related Macular Degeneration
Interventions
Other: Brolucizumab
First Posted Date
2022-03-04
Last Posted Date
2024-03-25
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
99
Registration Number
NCT05266495
Locations
🇦🇪

Novartis Investigative Site, Abu Dhabi, United Arab Emirates

Exploring the Profiles of RMS Patients on Ofatumumab or Ocrelizumab in a Real-World Setting in the Gulf

Active, not recruiting
Conditions
Relapsing Multiple Sclerosis
Interventions
Other: Ofatumumab
Other: Ocrelizumab
First Posted Date
2022-03-04
Last Posted Date
2024-07-26
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
168
Registration Number
NCT05266469
Locations
🇦🇪

Novartis Investigative Site, Sharjah, United Arab Emirates

A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)

Phase 4
Recruiting
Conditions
Renal Angiomyolipoma
Interventions
First Posted Date
2022-02-23
Last Posted Date
2024-10-21
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
10
Registration Number
NCT05252585
Locations
🇨🇳

Novartis Investigative Site, Taipei, Taiwan

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

First Posted Date
2022-02-11
Last Posted Date
2022-11-04
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
48
Registration Number
NCT05236530
Locations
🇬🇧

Novartis Investigative Site, Belfast, Northern Ireland, United Kingdom

Open-label Extension Study of Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Lupus Nephritis

Phase 3
Terminated
Conditions
Lupus Nephritis
Interventions
First Posted Date
2022-02-10
Last Posted Date
2024-02-02
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
31
Registration Number
NCT05232864
Locations
🇻🇳

Novartis Investigative Site, Ho Chi Minh, VNM, Vietnam

A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration

Phase 2
Recruiting
Conditions
Age-Related Macular Degeneration
Interventions
Drug: Iptacopan (LNP023)
Drug: Placebo
First Posted Date
2022-02-09
Last Posted Date
2024-06-25
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
146
Registration Number
NCT05230537
Locations
🇺🇸

Southwest Retina Research Center, Durango, Colorado, United States

🇺🇸

Advanced Research LLC Research, Deerfield Beach, Florida, United States

🇺🇸

Advanced Research LLC, Deerfield Beach, Florida, United States

and more 23 locations

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With Asthma

Phase 2
Recruiting
Conditions
Asthma
Interventions
Drug: Glycopyrronium bromide 25ug
Drug: Placebo
Drug: Glycopyrronium bromide 12.5ug
First Posted Date
2022-02-03
Last Posted Date
2024-06-25
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
42
Registration Number
NCT05222529
Locations
🇬🇧

Novartis Investigative Site, London, United Kingdom

Managed Access Programs for LNP023, Iptacopan

Conditions
C3 Glomerulopathy (C3G)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
First Posted Date
2022-02-03
Last Posted Date
2024-10-28
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT05222412
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