MedPath

Commons, Marty

🇺🇸United States
Ownership
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Employees
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Market Cap
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Website

Asciminib in Monotherapy for Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation

Phase 3
Completed
Conditions
Chronic Myelogenous Leukemia - Chronic Phase
Interventions
Drug: ABL001
First Posted Date
2020-12-14
Last Posted Date
2024-07-12
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
56
Registration Number
NCT04666259
Locations
🇺🇸

Univ of TX MD Anderson Cancer Cntr ., Houston, Texas, United States

🇺🇸

Uni of Cincinnati Medical Center ., Cincinnati, Ohio, United States

🇺🇸

Oncology Hematology Care Inc ., Cincinnati, Ohio, United States

and more 19 locations

A Multicenter Study to Assess Response to Influenza Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab

Phase 4
Completed
Conditions
Relapsing Multiple Sclerosis
Interventions
Biological: Quadrivalent influenza vaccine
Drug: iDMT
Drug: Ofatumumab
First Posted Date
2020-12-14
Last Posted Date
2024-10-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
63
Registration Number
NCT04667117
Locations
🇺🇸

The MS Center for Innovation in Care, Saint Louis, Missouri, United States

🇺🇸

Hope Research Institute Center Neurology and Spine, Phoenix, Arizona, United States

🇺🇸

Infinity Clinical Research LLC, Hollywood, Florida, United States

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C

Phase 2
Completed
Conditions
Hypercholesterolemia
Heterozygous Familial Hypercholesterolemia
Interventions
First Posted Date
2020-12-14
Last Posted Date
2024-06-20
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
312
Registration Number
NCT04666298
Locations
🇯🇵

Novartis Investigative Site, Saga, Japan

A First-in-human Study to Investigate the Safety, Tolerability and Pharmacokinetics of MAS825 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Placebo
Drug: MAS825
First Posted Date
2020-12-11
Last Posted Date
2022-09-30
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
80
Registration Number
NCT04665154
Locations
🇬🇧

Novartis Investigative Site, Mere Way, Nottingham, United Kingdom

A Non-interventional Study to Assess the Influence of Automated Optical Coherence Tomography Image Enrichment With Segmentation Information on Disease Activity Assessment in Patients Treated With Licensed Anti- VEGF Injections

Completed
Conditions
Neovascular Age-Related Macular Degeneration
Interventions
First Posted Date
2020-12-10
Last Posted Date
2024-06-18
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
494
Registration Number
NCT04662944
Locations
🇪🇸

Novartis Investigative Site, Leon, Spain

An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease Patients

Phase 4
Completed
Conditions
Sickle Cell Disease (SCD)
Interventions
First Posted Date
2020-12-10
Last Posted Date
2025-01-08
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
140
Registration Number
NCT04662931
Locations
🇮🇳

Novartis Investigative Site, Kolkata, West Bengal, India

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Phase 3
Active, not recruiting
Conditions
Familial Hypercholesterolemia - Homozygous
Interventions
Drug: Inclisiran
Drug: Placebo
First Posted Date
2020-12-09
Last Posted Date
2024-06-17
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
13
Registration Number
NCT04659863
Locations
🇺🇸

Excel Medical Clinical Trials LLC, Boca Raton, Florida, United States

🇱🇧

Hotel Dieu de France Hospital, Ashrafieh, Lebanon

🇹🇷

Novartis Investigative Site, Izmir, Turkey

and more 3 locations

Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

Phase 4
Recruiting
Conditions
Sickle Cell Disease
Interventions
First Posted Date
2020-12-08
Last Posted Date
2024-10-23
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
130
Registration Number
NCT04657822
Locations
🇺🇸

University Of Alabama, Birmingham, Alabama, United States

🇺🇸

Childrens National Hospital, Washington, District of Columbia, United States

🇺🇸

Augusta University Georgia Patient Treatment, Augusta, Georgia, United States

and more 5 locations

Digital Adherence Monitoring of Inhalative Therapy in Real- Life Conditions

Completed
Conditions
Asthma
Interventions
Combination Product: MF/IND/GLY plus sensor system
Drug: FDC therapy
First Posted Date
2020-12-07
Last Posted Date
2024-03-25
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
434
Registration Number
NCT04656223
Locations
🇩🇪

Novartis Investigative Site, Wiesbaden, Germany

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia

Phase 3
Active, not recruiting
Conditions
Familial Hypercholesterolemia - Heterozygous
Interventions
Drug: Inclisiran
Drug: Placebo
First Posted Date
2020-12-03
Last Posted Date
2024-08-12
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
141
Registration Number
NCT04652726
Locations
🇺🇸

Tucson Medical Center, Tucson, Arizona, United States

🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

🇺🇸

Wake Forest U of Health Sciences, Winston-Salem, North Carolina, United States

and more 28 locations
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