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Commons, Marty

🇺🇸United States
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Efficacy, Safety, Pharmacokinetics and Pharmacodynamics Study, Assessing Multiple LNP023 Doses in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria

Phase 2
Completed
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
Drug: LNP023
First Posted Date
2019-03-29
Last Posted Date
2024-06-18
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
13
Registration Number
NCT03896152
Locations
🇨🇳

Novartis Investigative Site, Taipei, Taiwan

Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

Phase 1
Active, not recruiting
Conditions
Nasopharyngeal Carcinoma
Microsatellite Stable Colorectal Cancer
Carcinoma, Non-Small-Cell Lung
Melanoma
Triple Negative Breast Cancer
Interventions
Drug: DKY709
Drug: PDR001
First Posted Date
2019-03-27
Last Posted Date
2025-01-10
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
99
Registration Number
NCT03891953
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Sarah Cannon Research Institute, Nashville, Tennessee, United States

and more 1 locations

Lipoprotein(a) in Patients With Cardiovascular Disease (CVD)

Not Applicable
Completed
Conditions
Cardiovascular Disease and Lipoprotein(a)
Interventions
Diagnostic Test: Blood draw for Lp(a)
First Posted Date
2019-03-25
Last Posted Date
2022-01-28
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
49001
Registration Number
NCT03887520
Locations
🇻🇳

Novartis Investigative Site, Ho Chi Minh, Vietnam

Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients

Phase 2
Active, not recruiting
Conditions
B-Cell Acute Lymphoblastic Leukemia
Interventions
Biological: CTL019
First Posted Date
2019-03-15
Last Posted Date
2024-07-26
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
121
Registration Number
NCT03876769
Locations
🇺🇸

Dana Farber Cancer Institute Dept.of DFCI, Boston, Massachusetts, United States

🇺🇸

Methodist Childrens Hospital ., San Antonio, Texas, United States

🇺🇸

City of Hope National Medical, Duarte, California, United States

and more 30 locations

Study of Tisagenlecleucel in Combination With Ibrutinib in r/r Diffuse Large B-cell Lymphoma Patients

Phase 1
Terminated
Conditions
Diffuse Large B-cell Lymphoma
Interventions
Biological: Tisagenlecleucel
Drug: Ibrutinib
First Posted Date
2019-03-15
Last Posted Date
2023-01-31
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
10
Registration Number
NCT03876028
Locations
🇺🇸

University of Pennsylvania, Abramson Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

De-escalation and TFR Study in CML Patients Treated With Nilotinib Followed by a Second Attempt After Nilotinib and Asciminib Combination

Phase 2
Active, not recruiting
Conditions
Chronic Myeloid Leukemia
Interventions
First Posted Date
2019-03-14
Last Posted Date
2024-11-14
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
124
Registration Number
NCT03874858
Locations
🇮🇹

Novartis Investigative Site, Novara, Italy

Study of Efficacy and Safety of Erenumab in Adult Chronic Migraine Patients

Phase 3
Active, not recruiting
Conditions
Migraine
Interventions
Other: Placebo
Biological: Erenumab
First Posted Date
2019-03-07
Last Posted Date
2024-04-02
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
557
Registration Number
NCT03867201
Locations
🇻🇳

Novartis Investigative Site, Hanoi, Vietnam

A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Phase 3
Completed
Conditions
Homozygous Familial Hypercholesterolemia
Interventions
Drug: Inclisiran Sodium for injection
Drug: Placebo
Drug: Placebos
First Posted Date
2019-02-22
Last Posted Date
2023-01-30
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
56
Registration Number
NCT03851705
Locations
🇷🇺

(50007-001) Research Institute of Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation

🇷🇸

(50381-001) Clinical Center of Serbia, Belgrad, Serbia

🇹🇷

(50090-001) Ege Universitesi, İzmir, Turkey

and more 10 locations

Study to Compare the Combination of Ribociclib Plus Goserelin Acetate With Hormonal Therapy Versus Combination Chemotherapy in Premenopausal or Perimenopausal Patients With Advanced or Metastatic Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
Drug: Ribociclib
Combination Product: Docetaxel / Capecitabine
Drug: Letrozole OR Anastrozole
Combination Product: Capecitabine / Vinorelbine
Combination Product: Paclitaxel / Gemcitabine
Drug: Goserelin
First Posted Date
2019-02-15
Last Posted Date
2024-10-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
223
Registration Number
NCT03839823
Locations
🇻🇳

Novartis Investigative Site, Hanoi, Vietnam

Study on Efficacy and Safety of LNP023 in C3 Glomerulopathy Patients Transplanted and Not Transplanted

Phase 2
Completed
Conditions
Glomerulonephritis
Interventions
Drug: LNP023
First Posted Date
2019-02-06
Last Posted Date
2024-01-30
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
27
Registration Number
NCT03832114
Locations
🇬🇧

Novartis Investigative Site, Newcastle Upon Tyne, United Kingdom

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