MedPath

Commons, Marty

🇺🇸United States
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Efficacy and Safety of Ofatumumab Compared to Placebo in Patients With Relapsing Multiple Sclerosis Followed by Extended Treatment With Open-label Ofatumumab

Phase 2
Completed
Conditions
Relapsing Multiple Sclerosis
Interventions
Drug: Matching placebo of ofatumumab
Drug: Ofatumumab
First Posted Date
2017-08-15
Last Posted Date
2022-04-29
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
64
Registration Number
NCT03249714
Locations
🇷🇺

Novartis Investigative Site, Novosibirsk, Russian Federation

Study to Investigate Whether AFQ056 Reduces Cocaine Use in Patients Diagnosed With Cocaine Use Disorder (CUD)

Phase 2
Completed
Conditions
Cocaine-related Disorder
Interventions
Drug: Placebo
Drug: AFQ056
First Posted Date
2017-08-08
Last Posted Date
2021-10-08
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
68
Registration Number
NCT03242928
Locations
🇨🇭

Novartis Investigative Site, Zuerich, Switzerland

Study of Oral cMET Inhibitor INC280 in Chinese Patients With EGFR Wild-type Advanced Non-small Cell Lung Cancer (NSCLC)

Phase 2
Withdrawn
Conditions
Carcinoma
Non-Small-Cell Lung Cancer
Interventions
Drug: INC280
First Posted Date
2017-08-07
Last Posted Date
2018-07-26
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT03240393

Study of Efficacy and Safety of QAW039 When Added to Standard-of-care Asthma Therapy in Patients With Uncontrolled Asthma

Phase 3
Completed
Conditions
Asthma
Interventions
Drug: Placebo
Drug: QAW039
First Posted Date
2017-07-21
Last Posted Date
2021-10-07
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
704
Registration Number
NCT03226392
Locations
🇻🇳

Novartis Investigative Site, Ho Chi Minh, Vietnam

ADCC Mediated B-Cell dEpletion and BAFF-R Blockade

Phase 2
Active, not recruiting
Conditions
Autoimmune Hepatitis
Interventions
Biological: VAY736
Other: Placebo
First Posted Date
2017-07-14
Last Posted Date
2024-12-24
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
68
Registration Number
NCT03217422
Locations
🇺🇸

Southern California Research Center, Coronado, California, United States

🇺🇸

Inland Empire Liver Foundation, Rialto, California, United States

🇺🇸

University of California Davis Medical Center, Sacramento, California, United States

and more 2 locations

Study of Efficacy and Safety of QAW039 When Added to Standard-of-care Asthma Therapy in Patients With Uncontrolled Asthma

Phase 3
Completed
Conditions
Asthma
Interventions
Drug: QAW039
Drug: Placebo
First Posted Date
2017-07-12
Last Posted Date
2021-10-07
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
675
Registration Number
NCT03215758
Locations
🇹🇷

Novartis Investigative Site, Yenisehir/Izmir, Turkey

A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

Phase 2
Terminated
Conditions
NSCLC, Non Small Cell Lung Cancer
RCC, Renal Cell Cancer
Head and Neck Cancer
Pancreatic Cancer
TNBC, Triple Negative Breast Cancer
Melanoma
mCRPC, Metastatic Castration Resistant Prostate Cancer
Urothelial Cancer
DLBCL, Diffused Large B Cell Lymphoma
MSS, Microsatellite Stable Colon Cancer
Interventions
Drug: NIR178
Drug: PDR001
First Posted Date
2017-07-05
Last Posted Date
2024-10-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
315
Registration Number
NCT03207867
Locations
🇺🇸

H Lee Moffitt Cancer Center and Research Institute ., Tampa, Florida, United States

🇺🇸

University of California, Los Angeles, Santa Monica, California, United States

🇨🇳

Novartis Investigative Site, Taipei, Taiwan

and more 3 locations

Effect of LIK066 on Reduction of Fatty Content in Livers of Obese Patients

Phase 2
Completed
Conditions
Obese Patients With Non-alcoholic Steatohepatitis (NASH)
Interventions
Drug: LIK066
Drug: Placebo
First Posted Date
2017-07-02
Last Posted Date
2021-10-08
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
107
Registration Number
NCT03205150
Locations
🇹🇭

Novartis Investigative Site, Bangkok, Thailand

Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)

Phase 2
Terminated
Conditions
Hereditary Hemochromatosis
Interventions
Drug: Deferasirox FCT
Procedure: Phlebotomy
First Posted Date
2017-06-29
Last Posted Date
2024-10-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
45
Registration Number
NCT03203850
Locations
🇨🇭

Novartis Investigative Site, Lugano, Switzerland

Study of Efficacy, Safety, and Quality of Life of Pazopanib in Patients With Advanced and/or Metastatic Renal Cell Carcinoma After Prior Checkpoint Inhibitor Treatment

Phase 2
Completed
Conditions
Advanced Renal Cell Carcinoma
Metastatic Renal Cell Carcinoma
Interventions
First Posted Date
2017-06-27
Last Posted Date
2023-08-21
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
62
Registration Number
NCT03200717
Locations
🇬🇧

Novartis Investigative Site, Preston, United Kingdom

🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

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