MedPath

Commons, Marty

🇺🇸United States
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Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- Intermediate Risk Early Breast Cancer

Phase 3
Withdrawn
Conditions
Breast Cancer
Interventions
Drug: Placebo
Drug: Ribociclib
Drug: Adjuvant endocrine therapy
First Posted Date
2017-03-16
Last Posted Date
2018-03-15
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT03081234

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- High Risk Early Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
Drug: Ribociclib
Drug: Adjuvant endocrine therapy
Drug: Placebo
First Posted Date
2017-03-13
Last Posted Date
2021-10-11
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
54
Registration Number
NCT03078751
Locations
🇺🇸

Memorial Regional Hospital, Hollywood, Florida, United States

🇺🇸

Northside Hospital Central Research Dept., Atlanta, Georgia, United States

🇺🇸

Tennessee Oncology, PLLC, Chattanooga, Tennessee, United States

and more 30 locations

Urine, DNA and Clinical Information Collection From Patients With Alport Nephropathy.

Completed
Conditions
Alport Nephropathy
First Posted Date
2017-03-08
Last Posted Date
2018-11-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
68
Registration Number
NCT03074357
Locations
🇺🇸

Novartis Investigative Site, Minneapolis, Minnesota, United States

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Phase 2
Withdrawn
Conditions
Basal Cell Carcinoma
Interventions
Drug: LDE225B
Drug: Vehicle
First Posted Date
2017-03-03
Last Posted Date
2017-05-05
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT03070691
Locations
🇬🇷

Novartis Investigative Site, Athens, Greece

🇬🇧

Novartis Investigative site, Manchester, United Kingdom

High Myopia: Extended and Longterm Observation of Pathologic Myopia Patients With the Risk for Developing a Myopic Choroidal Neovascularization (CNV)

Completed
Conditions
Pathologic Myopia
Interventions
Procedure: Observation & Diagnosis
First Posted Date
2017-03-03
Last Posted Date
2019-07-19
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
153
Registration Number
NCT03070717
Locations
🇩🇪

Novartis Investigative Site, Wuerzburg, Germany

A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF Patients

Phase 3
Completed
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
First Posted Date
2017-02-28
Last Posted Date
2021-10-11
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
2572
Registration Number
NCT03066804
Locations
🇬🇧

Novartis Investigative Site, York, United Kingdom

Study of PDR001 and/or MBG453 in Combination With Decitabine in Patients With AML or High Risk MDS

Phase 1
Completed
Conditions
Leukemia
Leukemia, Myeloid
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes
Preleukemia
Bone Marrow Diseases
Hematologic Diseases
Chronic Myelomonocytic Leukemia
Interventions
First Posted Date
2017-02-28
Last Posted Date
2024-08-29
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
241
Registration Number
NCT03066648
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

Oregon Health Sciences University Main Center, Portland, Oregon, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 1 locations

Study of Efficacy and Safety of Secukinumab in Subjects With Moderate to Severe Chronic Plaque-type Psoriasis

Phase 3
Completed
Conditions
Plaque Psoriasis
Interventions
First Posted Date
2017-02-28
Last Posted Date
2019-12-30
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
543
Registration Number
NCT03066609
Locations
🇹🇷

Novartis Investigative Site, Pendik / Istanbul, Turkey

PDR001 in Combination With Platinum-doublet Chemotherapy and Other Immunology Agents in PD-L1 Unselected, Metastatic NSCLC Patients

First Posted Date
2017-02-27
Last Posted Date
2022-08-15
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
111
Registration Number
NCT03064854
Locations
🇺🇸

UCLA Santa Monica Hematology / Oncology SC-2, Santa Monica, California, United States

🇺🇸

Henry Ford Health System SC, Detroit, Michigan, United States

🇺🇸

Stanford Cancer Center SC, Stanford, California, United States

and more 3 locations

Assess Bronchodilator Effect and Safety of Two Doses of QVM149 Compared to a Fixed Dose Combination of Salmeterol/Fluticasone in Patients With Asthma.

Phase 2
Completed
Conditions
Asthma
Interventions
Drug: QVM149 150/50/80 μg o.d.
Drug: QVM149 150/50/160 μg o.d.
Drug: salmeterol/fluticasone FDC 50/500 μg b.i.d.
First Posted Date
2017-02-24
Last Posted Date
2021-10-04
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
116
Registration Number
NCT03063086
Locations
🇬🇧

Novartis Investigative Site, Manchester, United Kingdom

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