A Dose Finding Study to Assess the Effect of LIK066 Compared to Placebo or Empagliflozin in Patients With Type 2 Diabetes Mellitus and Heart Failure
- Conditions
- Diabetes Mellitus and Heart Failure
- Interventions
- First Posted Date
- 2017-05-15
- Last Posted Date
- 2019-08-28
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 125
- Registration Number
- NCT03152552
- Locations
- π¬π§
Novartis Investigative Site, Birmingham, United Kingdom
Additive Effect of Twice-daily Brinzolamide 1%/Brimonidine 0.2%Combination as an Adjunctive Therapy to Travoprost in Patients With Normal Tension Glaucoma
- Conditions
- Glaucoma
- Interventions
- First Posted Date
- 2017-05-12
- Last Posted Date
- 2019-02-25
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 1
- Registration Number
- NCT03150160
- Locations
- π°π·
Novartis Investigative Site, Seoul, Korea, Republic of
A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder
- First Posted Date
- 2017-05-04
- Last Posted Date
- 2021-01-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 24
- Registration Number
- NCT03141086
- Locations
- πΊπΈ
Novartis Investigative Site, Cincinnati, Ohio, United States
A Bronchoprovocation Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CSJ117 in Adult Subjects With Mild Atopic Asthma
- First Posted Date
- 2017-05-03
- Last Posted Date
- 2021-10-12
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 28
- Registration Number
- NCT03138811
- Locations
- π©πͺ
Novartis Investigative Site, Mainz, Germany
Bronchodilator Effects and Safety of Glycopyrronium Bromide (25 ug and 50 ug o.d.) in Asthma
- Conditions
- Asthma
- Interventions
- Drug: NVA237 (glycopyrronium bromide)Drug: Placebo
- First Posted Date
- 2017-05-03
- Last Posted Date
- 2019-01-16
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 148
- Registration Number
- NCT03137784
- Locations
- π±πΉ
Novartis Investigative Site, Klaipeda, Lithuania
SKIPPAIN - Speed of Onset of SecuKinumab-Induced Relief From Pain in Patients With AxIal SpoNdyloarthritis
- Conditions
- Spondyloarthritis
- Interventions
- Biological: AIN457Drug: AIN457 Placebo
- First Posted Date
- 2017-05-02
- Last Posted Date
- 2021-09-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 383
- Registration Number
- NCT03136861
- Locations
- π¬π§
Novartis Investigative Site, Wolverhampton, United Kingdom
Study of PK/PD, Safety and Tolerability of LIK066 in Patients With Decreased Renal Function.
- First Posted Date
- 2017-04-27
- Last Posted Date
- 2021-01-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 53
- Registration Number
- NCT03131479
- Locations
- πΊπΈ
Novartis Investigative Site, Orlando, Florida, United States
A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease
- Conditions
- Alzheimers Disease
- Interventions
- Drug: CNP520 50mgDrug: CNP520 15mgOther: Matching placebo
- First Posted Date
- 2017-04-27
- Last Posted Date
- 2021-08-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 1145
- Registration Number
- NCT03131453
- Locations
- πΊπΈ
Meridien Research, 2300 Maitland center, Pkwy Ste 230, Maitland, Florida, United States
πΊπΈSyrentis Clinical Research, 1401 N Tustin Ave, Suite 130, Santa Ana, California, United States
π¬π§Novartis Investigative Site, London, United Kingdom
Phase III B in Acute Lymphoblastic Leukemia
- Conditions
- Acute Lymphoblastic Leukemia
- Interventions
- Biological: CTL019
- First Posted Date
- 2017-04-21
- Last Posted Date
- 2021-07-21
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 69
- Registration Number
- NCT03123939
- Locations
- πͺπΈ
Novartis Investigative Site, Esplugues de Llobregat, Barcelona, Spain
Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors
- Conditions
- Advanced EGFR Mutant Non Small Cell LungCancer (NSCLC)KRAS G12-mutant NSCLCEsophageal Squamous Cell Cancer (SCC)Head/Neck SCCMelanomaAdvanced Gastrointestinal Stromal Tumors (GIST)Advanced NRAS/BRAFT wt Cutaneous Melanoma
- Interventions
- Drug: TNO155 in combination with EGF816 (nazartinib)
- First Posted Date
- 2017-04-14
- Last Posted Date
- 2025-05-29
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 227
- Registration Number
- NCT03114319
- Locations
- πΊπΈ
H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States
πΊπΈDana Farber Cancer Center, Boston, Massachusetts, United States
πΊπΈMemorial Sloane Ketterin Cancer Ctr, New York, New York, United States