Glucarpidase Improves Kidney Recovery in Methotrexate-Associated Acute Kidney Injury
• A recent study found that glucarpidase treatment significantly improves kidney recovery in patients with methotrexate-associated acute kidney injury (AKI).
• Patients receiving glucarpidase showed a 2.7-fold higher odds of kidney recovery compared to those without glucarpidase, according to the study.
• Glucarpidase treatment was also associated with faster time-to-kidney recovery and reduced risks of neutropenia and transaminitis.
• The findings support the use of glucarpidase to improve renal and extrarenal outcomes in adults experiencing MTX-AKI.
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