Junlebao Dairy Group Co., Ltd.

Probiotic Supplementation Alters Gut Microbiota in Peritoneal Dialysis Patients

5 months ago

• A randomized, double-blind, placebo-controlled study investigated the impact of probiotic supplementation on gut microbiota in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). • The study found that _Lactobacillus paracasei_ N1115 (LP N1115) altered the diversity, abundance, and composition of gut microbiota in CAPD patients after 12 weeks of intervention. • However, the probiotic treatment did not significantly change fecal short-chain fatty acid (SCFA) levels in the study population. • The probiotic, LP N1115, was shown to be safe for consumption and well-tolerated in this patient population, with no serious adverse events reported.