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Galapagos

Galapagos logo
🇧🇪Belgium
Ownership
Public
Established
1999-01-01
Employees
1.1K
Market Cap
$1.9B
Website
http://www.glpg.com
Introduction

Galapagos NV is a biotechnology company, which engages in the identification and development of small molecule and antibody therapies. Its clinical pipeline includes filgotinib, GLP3667, Toledo program, and idiopathic pulmonary fibrosis. The company was founded by Onno van de Stolpe, Rudi Pauwels, and Helmuth van Es on June 30, 1999 and is headquartered in Mechelen, Belgium.

A Clinical Study to Test Long Term Safety of GLPG1690 for Patients With Systemic Sclerosis

Phase 2
Terminated
Conditions
Systemic Sclerosis
Interventions
Drug: GLPG1690
First Posted Date
2019-06-06
Last Posted Date
2022-03-29
Lead Sponsor
Galapagos NV
Target Recruit Count
31
Registration Number
NCT03976648
Locations
🇧🇪

UZ Gent, Gent, Belgium

🇪🇸

Hospital Universitario Vall d'Hebron, Barcelona, Spain

🇬🇧

Royal Free Hospital, London, United Kingdom

and more 11 locations

Study to Evaluate the Effect of Filgotinib on Semen Parameters in Adult Males With Active Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, or Non-radiographic Axial Spondyloarthritis

Phase 2
Completed
Conditions
Rheumatoid Arthritis
Psoriatic Arthritis
Ankylosing Spondylitis
Non-Radiographical Axial Spondyloarthritis
Interventions
Drug: Filgotinib
Drug: Placebo
Drug: Standard of Care
First Posted Date
2019-04-24
Last Posted Date
2024-04-30
Lead Sponsor
Galapagos NV
Target Recruit Count
109
Registration Number
NCT03926195
Locations
🇧🇬

DCC 17 - Sofia EOOD, Sofia, Bulgaria

🇧🇬

UMHAT Sv. Georgi, EAD, Plovdiv, Bulgaria

🇧🇬

MHAT "Eurohospital" - Plovdiv, OOD, Plovdiv, Bulgaria

and more 67 locations

A Study to Evaluate the Effects of a Single and Multiple Oral Doses of GLPG3121 in Adult, Healthy, Male Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo SAD
Drug: GLPG3121 SAD
Drug: GLPG3121 MAD
Drug: Placebo MAD
First Posted Date
2019-04-02
Last Posted Date
2019-07-05
Lead Sponsor
Galapagos NV
Target Recruit Count
31
Registration Number
NCT03899909
Locations
🇧🇪

SGS Belgium NV - Clinical Pharmacology Unit Antwerp, Antwerp, Belgium

A Study to Evaluate the Safety and Tolerability of MOR106 Administered Concomitantly With Topical Corticosteroids, in Adult Participants With Moderate to Severe Atopic Dermatitis

Phase 2
Terminated
Conditions
Atopic Dermatitis
Interventions
Drug: Placebo
Drug: MOR106
First Posted Date
2019-03-06
Last Posted Date
2021-01-05
Lead Sponsor
Galapagos NV
Target Recruit Count
33
Registration Number
NCT03864627
Locations
🇺🇸

Advanced Research Institute of Miami LLC, Homestead, Florida, United States

🇺🇸

Marvel Research, LLC, Huntington Beach, California, United States

🇺🇸

Arlington Dermatology, Rolling Meadows, Illinois, United States

and more 10 locations

A Study Investigating the Safety, Absorption and Elimination of GLPG3312, a New Drug in the Treatment of Inflammatory Diseases

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: GLPG3312 IR
Drug: Placebo
Drug: GLPG3312 MR
Drug: GLPG3312 FE MR
First Posted Date
2019-01-11
Last Posted Date
2020-03-19
Lead Sponsor
Galapagos NV
Target Recruit Count
95
Registration Number
NCT03800472
Locations
🇳🇱

PRA Health Sciences, Groningen, Netherlands

A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Systemic Sclerosis

Phase 2
Completed
Conditions
Systemic Sclerosis
Interventions
Drug: Placebo
Drug: GLPG1690
First Posted Date
2019-01-09
Last Posted Date
2021-05-04
Lead Sponsor
Galapagos NV
Target Recruit Count
33
Registration Number
NCT03798366
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Pacific Arthritis Care Center, Los Angeles, California, United States

🇺🇸

RASF Clinical Research Center, Boca Raton, Florida, United States

and more 15 locations

A Study in Healthy Male Volunteers to Look at How the Test Medicine GLPG1690 is Taken up by the Body When Given by Mouth and Into a Vein as an Injection

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: GLPG1690 film-coated tablets
Drug: [14C]-GLPG1690 capsules
Drug: [14C]-GLPG1690 solution for infusion
First Posted Date
2018-12-26
Last Posted Date
2019-02-15
Lead Sponsor
Galapagos NV
Target Recruit Count
8
Registration Number
NCT03787186
Locations
🇬🇧

Quotient Sciences Limited, Ruddington, United Kingdom

A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care

Phase 3
Terminated
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
Drug: GLPG1690
Drug: Placebo
First Posted Date
2018-11-07
Last Posted Date
2022-07-29
Lead Sponsor
Galapagos NV
Target Recruit Count
781
Registration Number
NCT03733444
Locations
🇺🇸

St. Francis Medical Institute, Clearwater, Florida, United States

🇺🇸

Emory University, Atlanta, Georgia, United States

🇺🇸

Piedmont Healthcare, Atlanta, Georgia, United States

and more 129 locations

A Clinical Study to Test How Effective and Safe GLPG1205 is for Participants With Idiopathic Pulmonary Fibrosis (IPF)

Phase 2
Completed
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
Drug: GLPG1205
Drug: Placebo
First Posted Date
2018-10-31
Last Posted Date
2021-09-14
Lead Sponsor
Galapagos NV
Target Recruit Count
68
Registration Number
NCT03725852
Locations
🇺🇦

The Ivano-Frankivsk National Medical Univeristy, Ivano-Frankivs'k, Ukraine

🇺🇦

Municipal Institution "Kherson city clinical hospital named after E.E. Karabelesh", Kherson, Ukraine

🇺🇦

Odessa Regional Hospital, Odessa, Ukraine

and more 33 locations

A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care

Phase 3
Terminated
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
Drug: GLPG1690
Drug: Placebo
First Posted Date
2018-10-18
Last Posted Date
2022-07-29
Lead Sponsor
Galapagos NV
Target Recruit Count
525
Registration Number
NCT03711162
Locations
🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

🇦🇺

Flinders Medical Centre, Bedford Park, Australia

🇦🇺

Box Hill Hospital, Box Hill, Australia

and more 129 locations
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