MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States
Ownership
-
Established
1811-01-01
Employees
-
Market Cap
-
Website
http://www.massgeneral.org/international
genengnews.com
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Patient Dies in Beam Trial of SCD Candidate; Company Cites Conditioning

Beam Therapeutics reported a patient death in a Phase I/II trial for BEAM-101, attributing it to the preconditioning regimen, not the treatment. The FDA allowed the trial to continue without changes. Researchers seek less toxic alternatives to busulfan, crucial in cell and gene therapy protocols.
financialpost.com
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Sonrai Accelerates Cancer Therapeutics Research with Advanced Analytics

Sonrai Analytics partners with MGH's Termeer Center to use Sonrai Discovery, a cloud-based AI platform, for integrating and analyzing multi-omics and clinical data, accelerating oncological research and personalized therapies.
urotoday.com
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Eligibility and Endpoints for Clinical Trials in Trimodality Therapy for Bladder Cancer

Trimodality therapy (TMT) for muscle-invasive localized bladder cancer aims to standardize trial eligibility criteria and endpoints, proposing bladder intact event-free survival (BIEFS) as a primary endpoint. An expert panel recommends pragmatic eligibility criteria and emphasizes patient-reported quality of life assessments to advance bladder preservation and treatment.
morningstar.com
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Hedonia's Mood Bloom™ Delivers the potential for Outsized Return on Investment in ...

Hedonia's Mood Bloom™ shows potential for 5:1 ROI, reducing costs and improving mental health outcomes, according to a study with Arbital Health. The study highlights significant cost savings for employers and insurers by treating depression and anxiety with the app, which uses a therapeutic gaming approach.
targetedonc.com
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Navigating ESR1 Mutations in HR-Positive Breast Cancer With Dr Wander

Seth Wander discusses the significance of ESR1 mutations in HR+ metastatic breast cancer, emphasizing the importance of ESR1 testing in clinical practice, particularly after standard antiestrogen therapy progression. He highlights the FDA approval of elacestrant, the role of liquid vs tissue biopsy, and the interpretation of variant allele frequency (VAF) in treatment decisions. Wander also mentions the SERENA-6 trial and the challenges in ESR1 mutation testing.
medicaleconomics.com
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AI can identify aggressive prostate cancer lesions; community engagement in genomics research

AI model identifies aggressive prostate cancer lesions, aiding diagnosis and treatment decisions. Workshop addresses sustaining community engagement in genomics research amidst historical unethical practices. Spine MRI diagnosis improves with patient symptom knowledge, enhancing accurate treatment decisions.
biospace.com
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First Patient In - BioPorto Initiates Patient Enrollment for US Study of ProNephro AKI (NGAL)

BioPorto initiates US study for ProNephro AKI (NGAL)™ at Massachusetts General Hospital to determine AKI risk stratification cut-off in adults, aiming for FDA clearance by 2026.
telegram.com
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UMass' Nobel win reflects strong life sciences ecosystem in Mass.

Victor Ambros and Gary Ruvkun won the 2024 Nobel Prize in Physiology or Medicine for discovering microRNA, marking UMass Chan Medical School's second Nobel in two decades. Massachusetts' $1 billion life sciences investment has led to significant advancements, including the RNA Therapeutics Institute. Gov. Maura Healey proposes another $1 billion investment to maintain the state's leadership in biotechnology. UMass Chan's research, including on C. elegans, has yielded therapies for various diseases, highlighting the value of science and investment in medical research.
neurologylive.com
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Friday 5 — October 25, 2024

NeurologyLive's Friday 5 covers updated stroke prevention guidelines, FDA approval for pediatric narcolepsy treatment, new RLS guidelines shifting from dopamine agonists, innovative educational approaches for neuromuscular specialists, and Medicare's impact on neurological care.
aacr.org
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AACR Industry Roundtable 2024: Detecting and Treating Cancer Early

The AACR Industry Roundtable 2024 discussed AI's potential in predicting lung cancer with Sybil, a deep learning model. The event highlighted collaborations between biopharmaceutical companies, researchers, and patient advocates, focusing on early cancer detection and treatment. Discussions included AI's integration challenges, patient advocate impacts, and trial design strategies for early cancers.
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