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Pharmacyclics LLC

Pharmacyclics LLC logo
🇺🇸United States
Ownership
Subsidiary
Established
1991-01-01
Employees
607
Market Cap
-
Website
http://www.pharmacyclics.com

Clinical Trials

116

Active:64
Completed:44

Trial Phases

3 Phases

Phase 1:84
Phase 2:19
Phase 3:11

Drug Approvals

1

FDA:1

Drug Approvals

Imbruvica

Approval Date
Feb 22, 2024
FDA

Clinical Trials

Distribution across different clinical trial phases (114 trials with phase data)• Click on a phase to view related trials

Phase 1
84 (73.7%)
Phase 2
19 (16.7%)
Phase 3
11 (9.6%)

Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD)

Phase 1
Active, not recruiting
Conditions
Chronic Graft Versus Host Disease
Interventions
First Posted Date
2018-12-31
Last Posted Date
2025-05-31
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
59
Registration Number
NCT03790332
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

Rady Children's Hospital, San Diego, California, United States

🇺🇸

University of California, San Francisco, California, United States

and more 45 locations

Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)

Phase 3
Completed
Conditions
Mantle-Cell Lymphoma
Interventions
Drug: Placebo Oral tablet to match Venetoclax
First Posted Date
2017-04-13
Last Posted Date
2024-07-01
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
352
Registration Number
NCT03112174
Locations
🇺🇸

The University of Arizona Cancer Centre-North Campus, Tucson, Arizona, United States

🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

UCLA Department of Medicine-Hematology/Oncology, Los Angeles, California, United States

and more 117 locations

Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD)

Phase 3
Completed
Conditions
Chronic Graft Versus Host Disease
Interventions
First Posted Date
2016-11-09
Last Posted Date
2023-03-30
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
193
Registration Number
NCT02959944
Locations
🇺🇸

Arizona Oncology - Scottsdale - Cancer Transplant Institute Location /ID# 1140-1120, Scottsdale, Arizona, United States

🇺🇸

LPCH Stanford /ID# 1140-1128, Palo Alto, California, United States

🇺🇸

Ucsf /Id# 1140-0003, San Francisco, California, United States

and more 99 locations

Study of Ibrutinib and Rituximab in Treatment Naïve Follicular Lymphoma

Phase 3
Active, not recruiting
Conditions
Follicular Lymphoma
Interventions
First Posted Date
2016-10-27
Last Posted Date
2025-01-24
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
445
Registration Number
NCT02947347
Locations
🇺🇸

Southern Cancer Center, Mobile, Alabama, United States

🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

Sansum Clinic, Santa Barbara, California, United States

and more 124 locations

Ibrutinib Plus Venetoclax in Subjects With Treatment-naive Chronic Lymphocytic Leukemia /Small Lymphocytic Lymphoma (CLL/SLL)

Phase 2
Completed
Conditions
Leukemia
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
First Posted Date
2016-09-22
Last Posted Date
2024-12-20
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
323
Registration Number
NCT02910583
Locations
🇺🇸

City of Hope /ID# 1142-0047, Duarte, California, United States

🇺🇸

Moores Cancer Center at UC San Diego /ID# 1142-0241, La Jolla, California, United States

🇺🇸

UC Irvine Medical Center - Chao Family Comprehensive Cancer Center /ID# 1142-0008, Orange, California, United States

and more 43 locations
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