University of Oxford

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Established: 1096-01-01

Employees: 10K

Market Cap: -

Website: http://www.ox.ac.uk

Clinical Trials

LITMUS Imaging Study

Active, not recruiting

Conditions: NASH
NASH - Nonalcoholic Steatohepatitis
Fibrosis, Liver
Steatosis of Liver
NAFLD

First Posted Date: 2022-07-29

Last Posted Date: 2024-05-16

Lead Sponsor: University of Oxford

Target Recruit Count: 450

Registration Number: NCT05479721

Locations: 🇪🇸
Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocío University Hospital, Sevilla, Spain
🇩🇪
Universitätsklinikums Würzburg, Würzburg, Germany
🇮🇹
Department of Medical Sciences University of Torino, Torino, Italy

and more 15 locations

Biomarkers Associated With Postoperative Cognitive Dysfunction

Recruiting

Conditions: Postoperative Cognitive Dysfunction
Cognitive Impairment
Cognitive Decline
Delirium

Interventions: Procedure: Intraoperative electroencephalography recording
Procedure: Neurofilament light chain measurement
Procedure: Tau protein measurement

First Posted Date: 2022-07-19

Last Posted Date: 2023-12-05

Lead Sponsor: University of Oxford

Target Recruit Count: 45

Registration Number: NCT05464355

Locations: 🇬🇧
Royal Berkshire NHS Foundation Trust, Reading, Berkshire, United Kingdom

A Study of Cardiovascular Events iN Diabetes Plus

Phase 4

Recruiting

Conditions: Diabetes Mellitus, Type 2

Interventions: Drug: Semaglutide Oral Tablet
Drug: Placebo oral tablet

First Posted Date: 2022-07-01

Last Posted Date: 2024-05-08

Lead Sponsor: University of Oxford

Target Recruit Count: 20000

Registration Number: NCT05441267

Locations: 🇬🇧
Clinical Trial Service Unit and Epidemiological Studies Unit, Oxford, United Kingdom

Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies

Not Applicable

Conditions: Pre-Eclampsia
Pregnancy Induced Hypertension
Pregnancy Related

Interventions: Dietary Supplement: Arcofolin® 5-Methyltetrahydrofolate
Dietary Supplement: Arcofolin® Placebo

First Posted Date: 2022-06-27

Last Posted Date: 2022-06-27

Lead Sponsor: University of Oxford

Target Recruit Count: 128

Registration Number: NCT05434195

Locations: 🇬🇧
Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordhsire, United Kingdom
🇬🇧
Cardiovascular Clinical Research Facility, Oxford, Oxfordshire, United Kingdom

Improving Vaccination in Older Adults by Inducing Autophagy With Spermidine

Not Applicable

Completed

Conditions: Vaccine Reaction
COVID-19

Interventions: Dietary Supplement: Spermidine or Placebo

First Posted Date: 2022-06-16

Last Posted Date: 2024-05-09

Lead Sponsor: University of Oxford

Target Recruit Count: 40

Registration Number: NCT05421546

Locations: 🇬🇧
University of Oxford, Oxford, United Kingdom

A Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UK

Early Phase 1

Conditions: Malaria
Plasmodium Falciparum

Interventions: Biological: Pfs48/45 in Matrix-M

First Posted Date: 2022-06-02

Last Posted Date: 2022-12-14

Lead Sponsor: University of Oxford

Target Recruit Count: 30

Registration Number: NCT05400746

Locations: 🇬🇧
CCVTM, University of Oxford, Oxford, United Kingdom

Functional and Ultrasound Guided Resection of Glioblastoma

Not Applicable

Recruiting

Conditions: Glioma Glioblastoma Multiforme

Interventions: Other: Additional pre- and intra-operative imaging
Other: Standard of Care

First Posted Date: 2022-06-01

Last Posted Date: 2022-06-01

Lead Sponsor: University of Oxford

Target Recruit Count: 357

Registration Number: NCT05399524

Locations: 🇬🇧
Addenbrookes Hospital, Cambridge University NHSFT, Cambridge, United Kingdom
🇬🇧
University Hospital, Coventry, Coventry, United Kingdom
🇬🇧
Queen's Medical Centre, Nottingham University Hospitals NHST, Nottingham, United Kingdom

and more 21 locations

Rural South and Southeast Asia Household Health Survey

Completed

Conditions: Infections
Risk Factors
Health Status
Noncommunicable Disease

First Posted Date: 2022-05-25

Last Posted Date: 2024-02-28

Lead Sponsor: University of Oxford

Target Recruit Count: 4747

Registration Number: NCT05389540

Locations: 🇧🇩
BangladeshBuilding Resources Across Communities (BRAC), Dhaka, Bangladesh
🇰🇭
Cambodia Action for Health Development (AHEAD), Battambang, Cambodia
🇲🇲
Medical Action Myanmar (MAM), Yangon, Myanmar

and more 1 locations

Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV

Phase 1

Active, not recruiting

Conditions: Malaria

Interventions: Biological: R21/Matrix-M™

First Posted Date: 2022-05-23

Last Posted Date: 2024-10-22

Lead Sponsor: University of Oxford

Target Recruit Count: 120

Registration Number: NCT05385510

Locations: 🇺🇬
MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda

A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of the Blood-stage Malaria Candidate Vaccines RH5.1 in Matrix-M and R78C in Matrix-M in Healthy UK Adults

Early Phase 1

Recruiting

Conditions: Malaria, Falciparum

Interventions: Biological: Matrix M with R78C and/or RH5.1

First Posted Date: 2022-05-23

Last Posted Date: 2023-12-18

Lead Sponsor: University of Oxford

Target Recruit Count: 36

Registration Number: NCT05385471

Locations: 🇬🇧
CCVTM, University of Oxford, Churchill Hospital, Oxford, United Kingdom

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