University of Oxford

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Established: 1096-01-01

Employees: 10K

Market Cap: -

Website: http://www.ox.ac.uk

Clinical Trials

Sulforaphane Supplementation Study

Not Applicable

Conditions: Obesity
Non-Alcoholic Fatty Liver Disease
Metabolic Syndrome

Interventions: Dietary Supplement: Sulforaphane extract

First Posted Date: 2020-04-28

Last Posted Date: 2022-06-07

Lead Sponsor: University of Oxford

Target Recruit Count: 60

Registration Number: NCT04364360

Locations: 🇬🇧
Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford, Oxfordshire, United Kingdom

Ivermectin Safety in Small Children

Phase 2

Recruiting

Conditions: Scabies

Interventions: Drug: Permethrin Cream
Drug: Oral ivermectin
Other: Placebo tablet
Other: Placebo cream

First Posted Date: 2020-04-02

Last Posted Date: 2024-05-21

Lead Sponsor: University of Oxford

Target Recruit Count: 399

Registration Number: NCT04332068

Locations: 🇧🇷
Alfredo da Matta Tropical Dermatology Foundation (FUAM), Manaus, Brazil
🇰🇪
Kenya Medical Research Institute, Kisumu, Kenya
🇬🇲
MRC Unit The Gambia, Banjul, Gambia

A Study of a Candidate COVID-19 Vaccine (COV001)

Phase 1

Active, not recruiting

Conditions: Coronavirus

Interventions: Biological: ChAdOx1 nCoV-19
Biological: MenACWY
Biological: ChAdOx1 nCoV-19 full boost
Biological: ChAdOx1 nCoV-19 half boost
Biological: MenACWY boost
Biological: ChAdOx1 nCoV-19 0.5mL boost
Biological: ChAdOx1 nCoV-19 0.5mL (3.5-6.5x10^10vp) late vaccine (LV)
Biological: ChAdOx1 nCoV-19 0.5mL (3.5-6.5x10^10vp) late vaccine two (LVT)
Drug: Paracetamol

First Posted Date: 2020-03-27

Last Posted Date: 2023-08-01

Lead Sponsor: University of Oxford

Target Recruit Count: 1090

Registration Number: NCT04324606

Locations: 🇬🇧
University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, United Kingdom
🇬🇧
University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom
🇬🇧
St Georges University Hospital NHS Foundation Trust, London, United Kingdom

and more 3 locations

Safety and Immunogenicity of RH5.1/Matrix-M in Adults and Infants Living in Tanzania

Phase 1

Completed

Conditions: Malaria,Falciparum

Interventions: Biological: RH5.1/Matrix-M

First Posted Date: 2020-03-23

Last Posted Date: 2024-11-22

Lead Sponsor: University of Oxford

Target Recruit Count: 60

Registration Number: NCT04318002

Locations: 🇹🇿
Ifakara Health Institute Clinical Trial Facility, Bagamoyo, Tanzania

Chloroquine/ Hydroxychloroquine Prevention of Coronavirus Disease (COVID-19) in the Healthcare Setting

Not Applicable

Completed

Conditions: COVID19
Acute Respiratory Illnesses
Coronavirus

Interventions: Drug: Placebo
Drug: Chloroquine or Hydroxychloroquine

First Posted Date: 2020-03-11

Last Posted Date: 2023-04-04

Lead Sponsor: University of Oxford

Target Recruit Count: 4652

Registration Number: NCT04303507

Locations: 🇰🇪
Mbagathi County Hospital, Nairobi, Kenya
🇲🇱
Hospital Of Mali, Bamako, Mali
🇵🇰
The Aga Khan University Hospital, Karachi, Pakistan

and more 22 locations

Gonococcal Vaccine Study in Key Populations in Kenya

Not Applicable

Completed

Conditions: Gonorrhea

Interventions: Biological: 4CMenB (Bexsero®) vaccine

First Posted Date: 2020-03-05

Last Posted Date: 2022-04-14

Lead Sponsor: University of Oxford

Target Recruit Count: 50

Registration Number: NCT04297436

Locations: 🇰🇪
KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya

Cardiovascular Function and Ribavirin PK/PD in Lassa Fever in Lassa Fever

Completed

Conditions: Lassa Fever

First Posted Date: 2020-02-26

Last Posted Date: 2021-10-13

Lead Sponsor: University of Oxford

Target Recruit Count: 158

Registration Number: NCT04285034

Locations: 🇳🇬
Owo Federal Medical Centre, Owo, Ondo State, Nigeria

Controlled Human Malaria Infection Transmission Model - Phase A

Phase 1

Suspended

Conditions: Malaria,Falciparum

Interventions: Biological: PfSPZ Challenge
Drug: Sulfadoxine-Pyrimethamine
Drug: Piperaquine
Drug: Artemether lumefantrine
Drug: Primaquine

First Posted Date: 2020-02-21

Last Posted Date: 2024-05-23

Lead Sponsor: University of Oxford

Target Recruit Count: 44

Registration Number: NCT04280692

Locations: 🇰🇪
KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya

Physician Optimised Post-partum Hypertension Treatment Trial

Not Applicable

Active, not recruiting

Conditions: Pre-Eclampsia
Gestational Hypertension

Interventions: Device: OMRON Evolv® blood pressure monitor (Blue-tooth® enabled) & Proprietary Smartphone POP-HT app®

First Posted Date: 2020-02-18

Last Posted Date: 2021-10-22

Lead Sponsor: University of Oxford

Target Recruit Count: 200

Registration Number: NCT04273854

Locations: 🇬🇧
Cardiovascular Clinical Research Facility, Dept of Cardiovascular Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom
🇬🇧
Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordhsire, United Kingdom

A Phase Ib/II Study of the Safety and Immunogenicity of the Candidate Rabies Vaccine ChAdOx2 RabG

Phase 1

Active, not recruiting

Conditions: Rabies

Interventions: Biological: ChAdOx2 RabG
Biological: Inactivated Rabies Vaccine

First Posted Date: 2020-02-17

Last Posted Date: 2023-09-06

Lead Sponsor: University of Oxford

Target Recruit Count: 174

Registration Number: NCT04270838

Locations: 🇹🇿
IHI Clinical Trial Facility, Bagamoyo, Tanzania

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