DeepMed Research

University of Oxford

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Established: 1096-01-01

Employees: 10K

Market Cap: -

Website: http://www.ox.ac.uk

Clinical Trials

Rotavirus Vaccine in Premature Babies

Completed

Conditions: Gastroenteritis

First Posted Date: 2014-09-29

Last Posted Date: 2017-05-09

Lead Sponsor: University of Oxford

Target Recruit Count: 20

Registration Number: NCT02252029

Locations: 🇬🇧
Department of Paediatrics, University of Oxford, Oxford, Oxfordshire, United Kingdom
🇬🇧
Oxford University Hospitals NHS Trust, Oxford, United Kingdom

Reformulated F75 Milk to Treat Severe Acute Malnutrition

Phase 2

Completed

Conditions: Malnutrition
Diarrhoea
Metabolic Disturbance

Interventions: Dietary Supplement: Standard F75 Milk
Dietary Supplement: Modified F75 Milk

First Posted Date: 2014-09-22

Last Posted Date: 2016-04-14

Lead Sponsor: University of Oxford

Target Recruit Count: 842

Registration Number: NCT02246296

Locations: 🇰🇪
Kilifi County Hospital, Kilifi, Coast, Kenya
🇲🇼
Queen Elizabeth Hospital- Study site, Blantyre, Malawi
🇰🇪
Coast Provincial General Hospital - Study site, Mombasa, Kenya

A Study to Assess New Ebola Vaccines, cAd3-EBO Z and MVA-BN® Filo

Phase 1

Completed

Conditions: Ebola
Ebola Zaire

Interventions: Biological: cAd3-EBO Z at 5 x 10^10 vp
Biological: cAd3-EBO Z at 1 x 10^10 vp
Biological: cAd3-EBO Z at 2.5 x 10^10 vp
Biological: 4.4x10^8 TCID50s MVA-BN® Filo
Biological: 2.2x10^8 TCID50s MVA-BN® Filo
Biological: 4.4 x 10^7 TCID50s MVA-BN® Filo

First Posted Date: 2014-09-16

Last Posted Date: 2018-07-06

Lead Sponsor: University of Oxford

Target Recruit Count: 91

Registration Number: NCT02240875

Locations: 🇬🇧
Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom

Causes and Factors Associated With Outcomes in Community-acquired Sepsis and Severe Sepsis in Northeast Thailand

Completed

Conditions: Severe Sepsis
Sepsis

First Posted Date: 2014-08-15

Last Posted Date: 2017-11-01

Lead Sponsor: University of Oxford

Target Recruit Count: 5020

Registration Number: NCT02217592

Locations: 🇹🇭
Sappasithiprasong Hospital, Ubon Ratchathani, Thailand

Comparison of the ECG Effects Related to Pharmacokinetic Profile of Chloroquine and Piperaquine

Phase 4

Completed

Conditions: Healthy

Interventions: Drug: Dihydroartemisinin-piperaquine
Drug: Chloroquine

First Posted Date: 2014-07-17

Last Posted Date: 2015-11-03

Lead Sponsor: University of Oxford

Target Recruit Count: 16

Registration Number: NCT02192944

Locations: 🇹🇭
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge Study

Not Applicable

Completed

Conditions: Paratyphoid Fever
Typhoid Fever

Interventions: Biological: Salmonella Typhi
Biological: Salmonella Paratyphi

First Posted Date: 2014-07-16

Last Posted Date: 2022-06-02

Lead Sponsor: University of Oxford

Target Recruit Count: 125

Registration Number: NCT02192008

Locations: 🇬🇧
Oxford Vaccine Group, Oxford, Oxfordshire, United Kingdom

Genetic Susceptibility to Rheumatic Heart Disease in the Pacific Region

Completed

Conditions: Rheumatic Heart Disease
Mitral Stenosis

First Posted Date: 2014-07-14

Last Posted Date: 2014-07-15

Lead Sponsor: University of Oxford

Target Recruit Count: 2372

Registration Number: NCT02188862

Locations: 🇫🇯
Colonial War Memorial Hospital, Suva, Fiji
🇳🇨
Centre Hospitalier Territorial de Nouvelle Caledonie, Noumea, New Caledonia
🇬🇧
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Targeted Chemotherapy Using Focused Ultrasound for Liver Tumours

Phase 1

Completed

Conditions: Liver Tumour

Interventions: Drug: ThermoDox® (LTLD)
Device: Focused Ultrasound of Target Liver Tumour
Diagnostic Test: Pre-LTLD Biopsy of Target Liver Tumour
Diagnostic Test: Post-LTLD Biopsy of Target Liver Tumour
Diagnostic Test: Post-LTLD+FUS (Post-FUS) Biopsy of Target Liver Tumour
Device: Thermometry of Target Tumour

First Posted Date: 2014-07-03

Last Posted Date: 2019-07-22

Lead Sponsor: University of Oxford

Target Recruit Count: 10

Registration Number: NCT02181075

Locations: 🇬🇧
Oxford University Hospitals NHS Trust, Oxford, United Kingdom

A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of New Plasmodium Falciparum Malaria Vaccine Candidates ChAd63 RH5 Alone and With MVA RH5

Phase 1

Completed

Conditions: Plasmodium Falciparum
Malaria

Interventions: Biological: ChAd63 RH5 low dose
Biological: ChAd63 RH5 full dose
Biological: MVA RH5 low dose
Biological: MVA RH5 full dose

First Posted Date: 2014-07-03

Last Posted Date: 2015-12-03

Lead Sponsor: University of Oxford

Target Recruit Count: 26

Registration Number: NCT02181088

Locations: 🇬🇧
Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, United Kingdom
🇬🇧
Wellcome Trust CRF, Southampton General Hospital, University of Southampton, Southampton, United Kingdom

Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents

Phase 2

Completed

Conditions: Tuberculosis

Interventions: Biological: MVA85A

First Posted Date: 2014-07-01

Last Posted Date: 2015-01-30

Lead Sponsor: University of Oxford

Target Recruit Count: 36

Registration Number: NCT02178748

Locations: 🇺🇬
MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda

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