CureVac

Country

Ownership: -

Employees: 1.1K

Market Cap: -

Website

Introduction: CureVac BV is a clinical-stage biopharmaceutical company, which engages in developing transformative medicines based on messenger ribonucleic acid (mRNA). Its product portfolio includes clinical and preclinical candidates across multiple disease indications in prophylactic vaccines, oncology, and protein therapy. The company was founded by Ingmar Hoerr and Florian von der Mülbe in 2000 and is headquartered in Tübingen, Germany.

Clinical Trials

RNActive® Rabies Vaccine (CV7201) in Healthy Adults

Phase 1

Completed

Conditions: Rabies

Interventions: Biological: CV7201 mRNA

First Posted Date: 2014-09-16

Last Posted Date: 2018-10-29

Lead Sponsor: CureVac

Target Recruit Count: 101

Registration Number: NCT02241135

Locations: 🇩🇪
Abteilung für Infektions- und Tropenmedizin der Ludwig-Maximilians-Universität, Munich, Germany

Safety and Tolerability of CV8102 Alone and in Combination With a Rabies Virus Vaccine in Healthy Adults

Phase 1

Completed

Conditions: Rabies

Interventions: Biological: CV8102
Biological: Rabipur
Biological: CV8102 + Rabipur

First Posted Date: 2014-09-12

Last Posted Date: 2018-06-06

Lead Sponsor: CureVac

Target Recruit Count: 72

Registration Number: NCT02238756

Locations: 🇩🇪
CRS Clinical Research Services Mönchengladbach GmbH, Mönchengladbach, Germany

An Open Label Randomised Trial of RNActive® Cancer Vaccine in High Risk and Intermediate Risk Patients With Prostate Cancer

Phase 2

Terminated

Conditions: Prostate Carcinoma

Interventions: Biological: CV9104
Device: needle free injection device (Tropis®)

First Posted Date: 2014-05-16

Last Posted Date: 2016-06-13

Lead Sponsor: CureVac

Target Recruit Count: 35

Registration Number: NCT02140138

Locations: 🇩🇪
Nationales Zentrum für Tumorerkrankungen, Medizinische Onkologie, Heidelberg, Baden-Württemberg, Germany
🇩🇪
Klinik für Urologie, Universitätsklinikum Tübingen, Tübingen, Baden-Württemberg, Germany
🇩🇪
Klinikum rechts der Isar, Urologische Klinik und Poliklinik der Technischen Universität München, München, Bayern, Germany

Trial of RNActive®-Derived Cancer Vaccine and Local Radiation in in Stage IV Non Small Cell Lung Cancer (NSCLC)

Phase 1

Terminated

Conditions: Non-Small Cell Lung Carcinoma

Interventions: Biological: CV9202
Radiation: local radiation

First Posted Date: 2013-08-05

Last Posted Date: 2016-08-05

Lead Sponsor: CureVac

Target Recruit Count: 26

Registration Number: NCT01915524

Locations: 🇩🇪
Klinikum Esslingen GmbH, Esslingen, Germany
🇩🇪
Thoraxklinik-Heidelberg gGmbH, Heidelberg, Germany
🇨🇭
Kantonspital St. Gallen, St. Gallen, Switzerland

and more 10 locations

Trial of RNActive®-Derived Prostate Cancer Vaccine in Metastatic Castrate-refractory Prostate Cancer

Phase 1

Terminated

Conditions: Prostate Cancer

Interventions: Biological: Placebo
Biological: CV9104

First Posted Date: 2013-03-25

Last Posted Date: 2017-02-17

Lead Sponsor: CureVac

Target Recruit Count: 197

Registration Number: NCT01817738

Locations: 🇩🇪
Urologische Klinik Dr. Castingius München, Planegg, Germany
🇩🇪
Universitätsklinik für Urologie, Tübingen, Germany
🇪🇸
Hospital de Madrid Norte Sanchinarro Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Spain

and more 45 locations

Trial of an RNActive®-Derived Cancer Vaccine in Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC)

Phase 1

Completed

Conditions: Non Small Cell Lung Cancer

Interventions: Biological: CV9201

First Posted Date: 2009-06-18

Last Posted Date: 2018-03-20

Lead Sponsor: CureVac

Target Recruit Count: 46

Registration Number: NCT00923312

Locations: 🇨🇭
UniversitätsSpital Basel, Basel, Switzerland
🇨🇭
UniversitätsSpital Zürich, Zürich, Switzerland
🇩🇪
RWTH Aachen, Aachen, Germany

and more 11 locations

Safety and Efficacy Trial of a RNActive®-Derived Prostate Cancer Vaccine in Hormone Refractory Disease

Phase 1

Completed

Conditions: Hormonal Refractory Prostate Cancer

Interventions: Biological: CV9103

First Posted Date: 2009-01-29

Last Posted Date: 2018-03-20

Lead Sponsor: CureVac

Target Recruit Count: 48

Registration Number: NCT00831467

Locations: 🇩🇪
Universitätsklinikum Aachen, Urologische Klinik, Aachen, Germany
🇩🇪
Universitätsklinikum Carl Gustav Carus der TU Dresden, Klinik und Poliklinik für Urologie, Dresden, Germany
🇩🇪
Charité Universitätsmedizin Berlin, Urologische Klinik u. Hochschulambulanz, Berlin, Germany

and more 9 locations

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